The hemocompatibility of blood-contacting medical devices remains one the major challenges in biomedical engineering and makes research field new improved materials inevitable. However, current in-vitro test analysis methods are still lacking standardization comparability, which impedes advances material design. For example, optical platelet tests is carried out manually or semi-manually by eac...

Aim: There are Conflicting reports on safety profile of nanoparticles biological cells. This study evaluated the impact nanosilver hemocompatibility salt-loaded rats. Materials and Methods: Sprague-Dawley rats [(inbred) (120-140 g)] randomly divided into 4 groups, (n = 6) were studied. Group 1(control) received normal rat chow tap water, 2 containing 8% NaCl [(salt-loaded (SLRs)]. 3 + Nanosilve...

Improving hemocompatibility of polypropylene via surface-initiated atom transfer radical polymerization for covalently coupling BSA Chunming Li , Jing Jin*, Jingchuan Liu, Xiaodong Xu, Jinghua Yin* State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China Graduate University of Chinese Academy of Scie...

The activation and adhesion of platelets or whole blood exposed to chitosan (CH) grafted surfaces is used to evaluate the hemocompatibility of biomaterials. The biomaterial surfaces are polyurethane (PU) tubes grafted with an inner poly(acrylic acid) (PAA) and an outer CH or quaternary ammonium modified CH (CH-Q) brush. The CH, CH-Q and PAA grafted layers were characterized by ellipsometry and ...

Germanium (Ge), as an elemental semiconductor material, has been an attractive candidate for manufacturing semiconductor microelectronic device. In the present investigation, to improve the biocompatibility of Ge-based device, graphene film is directly deposited on the Ge surface with different coverage area by controlling the growth time. Compared to bare Ge, the presence of graphene film enti...

Hydrogels (hylans) based on cross-linked hyaluronan (HA) are potentially good biomaterials for vascular tissue engineering applications because they are highly non-antigenic and -immunogenic. To facilitate surface endothelialization, vital to vascular deployment, we irradiated the gel surface with low wavelength UV light. This process micro-textures the smooth gel surface to provide sites for c...