نتایج جستجو برای: hemophilic arthropathy

تعداد نتایج: 7023  

Journal: :Journal of medical genetics 1985
F Bernardi L del Senno R Barbieri D Buzzoni R Gambari G Marchetti F Conconi F Panicucci M Positano S Pitruzzello

DNA from 20 Italian haemophilia B patients was analysed by the Southern blotting technique and hybridisation to a factor IX cDNA probe. A large deletion of factor IX gene was detected in one patient with antibodies to the infused factor; the EcoRI pattern of the other 19 subjects examined was normal.

Journal: :Nucleic acids research 1996
F. Giannelli P. M. Green S. S. Sommer M.-C. Poon M. Ludwig Rainer Schwaab Pieter H. Reitsma M. Goossens A. Yoshioka George G. Brownlee

The sixth edition of the haemophilia B database lists in easily accessible form all known factor IX mutations due to small changes (base substitutions and short additions and/or deletions of <30 bp) identified in haemophilia B patients. The 1380 patient entries are ordered by the nucleotide number of their mutation. Where known, details are given on factor IX activity, factor IX antigen in circ...

Journal: :The archives of bone and joint surgery 2017
Seyed Mohammad J Mortazavi Mohammad R Sobhan Hamed Mazoochy

Total knee arthroplasty (TKA) is a rewarding procedure in patients with hemophilia and end stage knee hemophilic arthropathy. However, this procedure might be associated with complications such as infection. There periprosthetic joint infection in patients with hemophilia is very well known, though we are not aware of any previous report on Brucella infection in this group of patients. Here, we...

Journal: :Blood 2015
Adrienne Lee Steven K Boyd Gregory Kline Man-Chiu Poon

Low bone density is a growing concern in aging men with hemophilia and may result in high-morbidity fragility fractures. Using high-resolution peripheral quantitative computed tomography (HR-pQCT), we demonstrate low trabecular and cortical bone density contributing to lower volumetric bone mineral density (BMD) at both distal radius and tibia in patients with hemophilia compared with age- and ...

2008
A. Amirabadi E. Miller L. Vidarsson M. S. Sussman H-L. M. Cheng A. S. Doria

Introduction: Hemophilia is an inherited bleeding disorder caused by deficiencies of clotting factors VIII and IX, respectively. Cartilage degeneration contributes to most of the disease morbidity. Early treatment of hemophilia has been shown to reduce long-term joint morbidity [1]. Novel functional MR imaging techniques hold the potential for being ideal diagnostic and prognostic tools for ass...

Journal: :Nucleic acids research 1990
F. Giannelli P. M. Green S. S. Sommer M.-C. Poon M. Ludwig Rainer Schwaab Pieter H. Reitsma M. Goossens A. Yoshioka M. S. Figueiredo George G. Brownlee

The seventh edition of the haemophilia B database lists in easily accessible form all known factor IX mutations due to small changes (base substitutions and short additions and/or deletions of <30 bp) identified in haemophilia B patients. The 1535 patient entries are ordered by the nucleotide number of their mutation. Where known, details are given on: factor IX activity, factor IX antigen in c...

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