Background: Systemic amyloidosis is characterized by amyloid deposition that can involve virtually any organ. Splenic and hepatic occurs in certain types, some patients but not others, may influence prognosis treatment. SAP (serum P component) scintigraphy uniquely able to identify quantify the liver spleen, thus informing clinical management, it only available 2 centers globally. The aims of t...

A 33-year-old black male, was referred to our department in 1981 for the following symptoms consistent with typical SCLS: several episodes of shock with generalized oedema; diffuse pain; and transient anuria. A monoclonal gammapathy of undetermined significance (MGUS) was discovered at that time. Three years later, he had minimal proteinuria (monoclonal component). Femoral artery superficializa...

Relatively little interes t is evident in the study of visceral manifes tations of leprosy, in spi te of their clinical importance ( 1), The liver might be expected to be the organ most freguently affected; it is responsible for plasma protein alterations, e.g. , effective albumin reduction and globulin increase, Histologic reports show that hepatic lesions in lepromatous leprosy are characteri...

Fig 1. Squamous cell carcinoma identified after multiple biopsy specimens of poorly healing area over left E pidermolysis bullosa (EB) consists of a heterogeneous group of autosomal dominant or recessive disorders, characterized by epithelial fragility. In dystrophic EB, patients have a genetic defect in the gene encoding collagen VII, COL7A1. Generalized severe recessive dystrophic EB (RDEB) i...