Background and objectives: The present work aimed to evaluate the acute toxicity of Aeollanthus pubescens essential oil, whose antimicrobial activity has been proven in vitro by previous studies and to examine the effects of this essential oil on the biochemical parameters (transaminases ALT and AST, urea, creatinine and cholesterol) and hematological and histological ...

Objective: Dalbegia saxatilis (D.saxatilis) is used as a decoction in traditional medicine for ailments such as cough, small pox, skin lesions, bronchial ailments and toothache. This study is aimed at evaluating the toxic effect of methanol leaf extract of D.saxatilis on renal function. Materials and Methods: Wistar rats of both sexes were divided into four groups of five: control animals (grou...

Splanchnic and renal net balance measurements indicate that lactate and glycerol may be important precursors for epinephrine-stimulated gluconeogenesis (GNG) in liver and kidney, but the effects of epinephrine on their renal and hepatic conversion to glucose in humans have not yet been reported. We therefore used a combination of renal balance and isotopic techniques in nine postabsorptive volu...

Objective(s):Acute kidney injury (AKI), a syndrome characterized by decreased glomerular filtration, occurs in every 1 of 5 hospitalized patients.  Renal ischemia-reperfusion, one of the main causes of AKI, is of particular importance in the setting of kidney transplantation. Materials and Methods: Sixty male rats were divided into four groups including control, nephrectomy, sham surgery and re...

The elderly population has significantly increased in China. However, data regarding renal histopathology in this population is lacking. The present study retrospectively analyzed renal disease spectrum of 430 elderly patients who had received renal biopsy at Peking University First Hospital between January 2003 and December 2012. Among 6049 patients receiving renal biopsies during the same per...

somatostatin-like immunoreactivity (SLI) was assessed simultaneously in an in vivo dog model. The hepatic extraction of this peptide was 29.4+±2.3% and was similar for endogenous and infused exogenous SLI. The renal extraction was 62.3±+5%. The renal clearance of SLI was significantly greater than that of inulin indicating that the peptide is handled by peritubular uptake from postglomerular bl...

Hepatic cirrhosis with portal hypertension and gastroesophageal hemorrhage is a disease complex that continues to be treated by surgical portasystemic shunts. Whether or not a reduction or diversion of portal blood flow to the liver adversely affects the ability of the liver to maintain fuel homeostasis via gluconeogenesis, glycogenolysis, and ketogenesis is unknown. 11 patients with biopsy-pro...

It is now common practice to undertake ultrasonography as the initial investigation of the renal tract but the finding of multiple hyperechoic tumours was quite unexpected. Such marked hyperechogenicity indicates a markedly fatty or fibrous consistency and excludes multiple cystic disease. Multiple well defined tumours in both kidneys is very suggestive ofangiomyolipomas, a benign hamartomatous...

advancements in medical science have led to the development of complex surgeries that improve survival in patients with liver disease. assessments of the indications and contraindications for surgery and risk factors are the most important steps prior to any surgery in this population. particular attention is essential to assess for the presence of pre-surgical ascites, hepatic encephalopathy a...

Background & Objective: Abdominal cutaneous and subcutaneous nodules are uncommon lesions which may be benign or malignant. Majority of the malignant nodules are metastatic in origin and may be the initial presentation of primary malignancy, hence an early diagnosis is important. Our aim was to find out the spectrum of lesions (both non-neoplastic and neoplastic) that present as cutaneous and s...