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background and aims: many studies have provided evidence for the role of hepatitis b and c viruses in the development of liver cancer. although the routine treatment is available for both conditions, no definite guideline is available to treat patients dually infected with hbv and hcv. this study was performed to determine the frequency of hbv/hcv-coinfection in mashhad, north-east of iran. mat...

conclusions based on our results, it seems that there were no cases of obi among chronic hcv-infected patients with thalassemia and bleeding disorders, particularly hemophilia. however, to improve decisions concerning obi screening, especially in transfusion centers, and concerning the use of comprehensive screening methods, more original studies with more precise laboratory techniques and larg...

The infectious hepatitis B virus represents 42 nm spherical double-shelled particles. However, analysis of blood from hepatitis B virus carriers revealed the presence of smaller 22 nm particles consisting of a viral envelope surface protein. These particles are highly immunogenic and have been used in the design of hepatitis B virus vaccine produced in yeast. Upon expression in yeast, these pro...

Chronic hepatitis B is still a major public health issue despite the successful prophylactic vaccination attempts. Chronicity of hepatitis B virus(HBV) is mainly due to its ability to debilitate host's immune system. Therefore, major measures have been taken to stop this process and help patients with chronic hepatitis B infection recover from their illness. While satisfactory results have been...

Potent antivirals are used for the treatment of hepatitis B infection. A 38-year-old female patient whose hepatit virus (HBV) viral load was suppressed under tenofovir disoproxil fumarate but had a flare during in vitro fertilization (IVF) is presented. Although HBV DNA negative continuously controls, an increase observed IVF treatment. Hepatitis has been isolated from many extrahepatic tissues...

conclusions we introduced an anti-hbsp antibodies elisa, designed for locally circulating hbv strains. correlation observed of anti-hbsp with liver fibrosis staging regardless of viral replication and liver inflammation suggests anti-hbsp antibodies as possible indicator for hbv-associated liver fibrosis. results seven out of eighty (9%) chb patients were positive for anti-hbsp antibodies. mean...

results the tt virus infection was significantly found in 40 of 95 (42.1%) and 12 of 100 (12%) patients with leukemia and controls, respectively. the hbs-ag and hcv-ab were detected in 27 of 95 (28.4%) and 18 of 69 (26.1%) patients with leukemia but were not found in the controls. active cmv infection was also found in 11 of 69 (16%) patients and none of the controls. significant co-infection o...