Human hepatocellular carcinoma is one of the most common recurrent malignancies, for as much as, there is no effective therapy. Silibinin, a widely used drug and supplement for various liver disorders, demonstrated anticancer effects against human hepatocellular carcinoma, human prostate adenocarcinoma cells, human breast carcinoma cells, human ectocervical carcinoma cells, and human colon canc...

Human hepatocellular carcinoma is one of the most common recurrent malignancies, for as much as, there is no effective therapy. Silibinin, a widely used drug and supplement for various liver disorders, demonstrated anticancer effects against human hepatocellular carcinoma, human prostate adenocarcinoma cells, human breast carcinoma cells, human ectocervical carcinoma cells, and human colon canc...

Abstract Background Hepatocellular carcinoma (HCC) can grow in a mosaic pattern, often combined with various non-hepatocellular cells. However, HCC neuroendocrine (NEC) component is rarely reported, and its clinical features, origin, diagnosis, behavior have not been established. In the literature, mixed HCC–NEC tumors are categorized as either collision type or type, depending on their microsc...

context hepatocellular carcinoma (hcc) is one of the most common cancers in the world but with a striking geographical variation in incidence; most of the burden is in developing countries. this geographic variation in hcc incidence might be due to geographic differences in the prevalence of various etiological factors. evidence acquisition here, we review the epidemiological evidence linking d...

of major hepatectomy for hepatocellular carcinoma associated with cirrhosis. Objective: To deWne the safety of major hepatectomy for hepatocellular carcinoma (HCC) associated with cirrhosis and the selection criteria for surgery in terms of hospital mortality.

Hepatocellular carcinoma (HCC) is a primary liver cancer that occurs due to the abnormal growth of hepatocytes. HCC one cancers with highest prevalence and incidence in world. The main risk factors for Indonesia are chronic infection hepatitis B virus, C cirrhosis. selection appropriate treatment modality each patient based on several patient-specific characteristics, such as tumor size, locati...

Successive current trials using immune response checkpoint blockade, the systemic therapy for progressive hepatocellular carcinoma (HCC) has shifted dramatically towards targeting tumor microenvironment (TME). Locoregional therapies (LRTs) like radiofrequency ablation (RFA)/rhizotomy, trans-arterial chemoembolization (TACE) and surgical resection in initial stages are critical. LRTs perform cru...

The TERT gene encodes its catalytic subunit that is essential for telomere length at the chromosome ends. expression of highly associated with risk human cancers. Recurrent mutations in promoter are identified as a mechanism to activate telomerase cancer. This study aims determine rate hepatocellular carcinoma (HCC) tissue samples and association between some factors HCC. was conducted on 84 pa...

According to the WHO’s recently released worldwide cancer data for 2020, liver ranks sixth in morbidity and third mortality among all malignancies. Hepatocellular carcinoma (HCC), most common kind of cancer, accounts approximately 80% primary malignancies is one leading causes death globally. The intractable tumor microenvironment plays an important role development progression HCC three major ...

Non-alcoholic fatty liver disease (NAFLD) is rapidly emerging as a leading etiology of chronic (CLD) in Asia. The increasing incidence NAFLD projected to drive surge NAFLD-related hepatocellular carcinoma (HCC). A notable characteristic NAFLD-HCC its capacity for development individuals without cirrhosis more than third patients. Most practice guidelines recommend biannual ultrasound screening ...