Background and objectives: Hypericum perforatum L., commonly known as St. John’s wort (SJW) from the family Hypericaceae is a famous medicinal plant used to treat mild to moderate depression; so, it might affect the pharmacokinetics of numerous drugs. Due to widespread herb-drug interactions of SJW, this study was designed to review the clinical evidences regarding the...

The main effects and interactions of four different mineral N levels (0, 50, 100 and 150kg fed -1 ) and four various poultry manure rates (0, 10, 15 and 20m 3 fed -1 ) on the vegetative growth, flowering, volatile oil content and chemical composition of marigold plants (Tagetes minuta) were investigated through two field experiments in 2000/2001 and 2001/2002. The obtained results, obviously, s...

Multi-herb therapy has been widely used in Traditional Chinese medicine and tailored to meet the specific needs of each individual. However, the potential molecular or systems mechanisms of them to treat various diseases have not been fully elucidated. To address this question, a systems pharmacology approach, integrating pharmacokinetics, pharmacology and systems biology, is used to comprehens...

Pharmacognosy Research,2022,14,4,461-467.DOI:10.5530/pres.14.4.67Published:October 2022Type:Original ArticleAuthors:Afnan Bahha, Aeshah Habib, Awsaf Alluqmani, Afnan Alqurashi, Ahlam Alotaibi, Yosra Al-Hindi, and Arwa Fairaq Author(s) affiliations:Afnan Bahha1, Habib1, Alluqmani1, Alqurashi1, Alotaibi1, Al-Hindi2 Fairaq3 1Pharm D Candidate, Faculty of Pharmacy, Umm Al-Qura University, Makkah, S...

Close proximity interactions (CPIs) measured by wireless electronic devices are increasingly used in epidemiological models. However, no evidence supports that electronically collected CPIs inform on the contacts leading to transmission. Here, we analyzed Staphylococcus aureus carriage and CPIs recorded simultaneously in a long-term care facility for 4 months in 329 patients and 261 healthcare ...

introduction: interaction between drugs represents a major clinical concern for health care professionals and their patients. patients affected by both type 2 diabetes and epilepsy may be prescribed pioglitazone and an anti-epileptic drug such as phenytoin  concurrently. the aim of this study was to consider the interaction of pioglitazone with phenytoin in an experimental model. according to t...