Osteogenesis imperfecta (OI) or Brittle bone disease is the most common genetic cause of osteoporosis. The OI is caused by structural or quantitative defect in type I collagen. OI has the triad of fragile bone, blue sclerae and early deafness. O1 type V is characterized by recurrent multiple fractures in a child following ambulation with hyperplastic callus formation at the sites of fracture. T...

A healthy 22-year-old man developed acute varicella pericarditis, characterised by an enanthem with diagnostic rising titres of varicella zoster antibodies but without the typical exanthem. This, the third reported case of varicella pericarditis, is the first to be documented without a typical varicella eruption.

TOPIC The incidence and morbidity of herpes zoster (HZ) and HZ ophthalmicus (HZO), and the potential impact of varicella vaccine on their epidemiology. CLINICAL RELEVANCE Herpes zoster affects 20% to 30% of the population at some point in their lifetime; approximately 10% to 20% of these individuals will have HZO. METHODS The peer-reviewed literature published from 1865 to the present was r...