IgG viral antibodies for herpes simplex virus -1, varicella zoster virus, cytomegalovirus, measles and mumps were studied in 76 subjects with obsessive compulsive disorder and compared with a control population. There was a significantly higher titre for some of the antibodies, most specifically for herpes simplex virus type 1 and mumps. This suggests a possible role for these viral infections ...

As one of the most common sexually transmitted diseases, genital herpes is a global medical problem with significant physical and psychological morbidity. Genital herpes is caused by herpes simplex virus type 1 or type 2 and can manifest as primary and/or recurrent infection. This manuscript provides an overview about the fundamental knowledge on the virus, its epidemiology, and infection. Furt...

BHK-21 cells infected with temperature-sensitive mutants of herpes simplex virus type 1 strain KOS representing 16 complementation groups were tested for susceptibility to complement-mediated immune cytolysis at permissive (34 degrees C) and nonpermissive (39 degrees C) temperatures. Only cells infected by mutants in complementation group E were resistant to immune cytolysis in a temperature-se...

We describe a case of chronic atypical herpes simplex type 2 encephalitis in an immunocompromised 68 year old man presenting with headache and cognitive changes without focal neurological or MRI findings. To our knowledge this is the first described case of herpes simplex encephalitis associated with normal MRI brain imaging and non-focal neurological examination. This further expands the range...

brown alga, turbinaria conoides was successively extracted with n-hexane, cyclohexane, methanol and ethanol:water (1:1). the extracts were evaluated for antibacterial and antifungal activities by disc diffusion method. minimal inhibitory concentration was determined for active extracts by broth dilution method. the antiviral activity and cytotoxicity of the extracts were tested in human embryon...

Inhibitors of cell enzyme Inosine 5 ́-Monophosphate (IMP) dehydrogenase – Ribavirine (Rbv), Micophenolic acid (MPA) and Mizoribine (MZR) have potential application as antiherpes agents in combination with acyclovir (ACV). The effectivity of action of ACV on herpesvirus replication is improved after decreasing of the concentration of dGTP as a result of IMP dehydrogenase inhibition. The antiviral...

background and aims: sexually transmitted infections (stis) are of major concern to clinicians and researchers in the field of reproductive medicine. many sti pathogens cause incurable and often fatal diseases, and have been transmitted through insemination procedures. the role of herpes simplex virus in male infertility has been investigated using the sensitive methods. the aim of this study w...

The first Russian clinical case of monkeypox in combination with herpes simplex type 1 infection a 29-year-old man who returned from Portugal is described. protocols for sequencing the virus genome are presented. Particular attention paid to difficulty diagnosing vesicular rash patients suspicious history.

herpes simplex virus type 1 establishes a latent infection in the peripheral nervous system following primary infection. during latent infection, virus genome exhibit limited transcription, with the hsv lats consistently detected in latency infected ganaglia. following ocular infection viral latency develops in the trigeminal ganglia. in this study pcr has been used for detection of hsv-1 nucli...

purpose: to evaluate the effectiveness of corneal collagen cross-linking with uv-a and riboflavin (cxl) for treatment of refractory herpes simplex virus necrotizing keratitis. case reports: two patients with a diagnosis of hsv necrotizing stromal keratitis referred to khalili hospital eye emergency room and who were resistant to conventional treatment underwent cxl. response to treatment was ev...