2 Varicella-zoster virus (VZV) is a human alphaherpesvirus that infects sensory ganglia 3 and reactivates from latency to cause herpes zoster. VZV replication was examined in human 4 dorsal root ganglia (DRG) xenografts in mice with severe combined immunodeficiency using 5 multiscale correlative immunofluorescence and electron microscopy (IF-EM). These 6 experiments showed the presence of VZV g...

: The reactivated form of the varicella-zoster virus (VZV) is responsible for chickenpox, known as herpes zoster (HZ). Although it a self-limiting infection, presents debilitating and painful mucosal dermal vesicular eruptions. Early identification management are vital to curbing spread HZ infection. In this extensive review, we present an overview HZ, including its structure, pathophysiology, ...

Latency within the nervous system is a characteristic feature of herpesviridae infection. It is reactivated by triggering factors such as UV exposure, stress, and trauma. Simultaneous reactivation of herpes simplex and herpes zoster is uncommon, however, an observation provably explained by differences in the triggering mechanism. Concurrent reactivation of herpes simplex virus (HSV) and varice...

There are six herpes viruses, three of which, the varicella-zoster virus and the herpes simplex viruses types 1 and 2, are of particular concern to patients and staff in critical care units. These viruses, especially in their reactivated states, may present atypically in critically ill and immune-suppressed patients, and, by the time the diagnosis is made, exposures of other patients and clinic...

Definition Varicella-zoster virus (VZV), also known as Human Herpes Virus III (HHVIII), is a member of the herpes virus group. As all the other viruses from this group, VZV can manifests itself as a recurrent infection. After entering the body and causing primary infection, varicella-zoster virus remains latent in the neurons of sensory ganglion, especially dorsal roots of ganglion of the spina...

The varicella-zoster virus (VZV) is a virus of the subfamily of Alfavirus responsible for infections with different clinical presentations. Primary infection occurs more frequently in the pediatric age presented as chickenpox. The reactivation of the infection occurs mainly in immunosuppressed patients, in the form of Herpes-Zoster [1]. Varicella-Zoster virus is associated with severe neurologi...

Vaccination against chickenpox causes a varicella-like rash in up to 5% of healthy children and 50% of children with leukemia. The vaccine may establish latency and reactivate to cause herpes zoster, albeit more rarely than wild-type virus. All vaccine preparations are composed of a mixture of varicella-zoster virus strains that show genotypic variation at several loci. We have shown, by DNA se...

BACKGROUND Herpes Zoster is a disease that occurs after the virus is reactivated due to infection of the varicella virus in childhood. Risk factors are advanced age, malignant neoplasm, organ transplantation, immunosuppressive agents taking are known. The purpose of this study was to investigate the relationship between the seasonal effect and other risk factors on the incidence of herpes zoste...

Ill or immunosuppressed hospital patients are at increased risk for herpes simplex and herpes zoster virus infections, with high potential morbidity and mortality. Here, we present two cases of reactivation of herpes virus infections with delay in diagnosis, with ultimately fatal results. Since these infections are treatable, it is important to keep a high index of suspicion to facilitate early...