idiopathic inflammatory myopathies are a heterogeneous group of muscle disorders characterized by chronic muscle inflammation and progressive muscle weakness. polymyositis (pm), dermatomyositis (dm) and inclusion body myositis (ibm) are the three major subsets based on distinct clinical and histopathological features. since the pathogenesis remains unclear, therapeutic approaches actually compr...

hereditary sensory and autonomic neuropathies (hsan) are clinically and genetically a heterogeneous group of disorders. there are overlapping variants of hsan regarding clinical manifestations and pathologic findings. five types of hsan have been described by dyck (1993) and there are two other types which have been introduced recently. we report four siblings that seem to suffer from symptomat...

Heterogeneous robot groups are a promising research direction for automating diverse tasks. A functional diierence between individual robot capabilities is likely to allow task-based specialization within the group. We report on experiments with a mechanically heterogeneous robot group consisting of a robotic helicopter and multiple wheeled ground robots. We present a behavior-based control sys...

Several studies have demonstrated that mesenchymal stem cells have the capacity to reverse acute and chronic kidney injury in different experimental models by paracrine mechanisms. This paracrine action may be accounted for, at least in part, by microvesicles (MVs) released from mesenchymal stem cells, resulting in a horizontal transfer of mRNA, microRNA and proteins. MVs, released as exosomes ...

In this paper, a group consensus problem is investigated for the heterogeneous agents that are governed by the Euler–Lagrange system and the double-integrator system, respectively, and the parameters of the Euler–Lagrange system are uncertain. To achieve group consensus, a novel group consensus protocol and a time-varying estimator of the uncertain parameters are proposed. By combining algebrai...

Recent developments of the enhanced hardware on mobile devices such as quad-core CPUs and various sensors have made it possible to build a powerful heterogeneous mobile cloud o„oading service that consists of a mobile ad-hoc cloud, nearby servers and public cloud services. However, the availability and mobility management of mobile devices in the network can signi€cantly hinder the performance ...

Single-molecule studies that allow to compute pKa values, proton affinities (gas-phase acidity/basicity) and the electrostatic energy of solvation have been performed for a heterogeneous set of 26 organic compounds. Quantum mechanical density functional theory (DFT) using the Becke-half&half and B3LYP functionals on optimized molecular geometries have been carried out to investigate the energet...

PDVM (Parallel and Distributed Virtual Machine) is a runtime environment targeted at the execution of parallel programs in a heterogeneous architecture composed of distributed-memory multiprocessors and uniprocessors connected by a local area network. The most distinctive feature of PDVM is its support for group-based communication primitives. Several dimensions arise when defining a group-base...

A dramatic difference is observed in the intracellular distribution of the high mobility group (HMG) proteins when chicken embryo fibroblasts are fractionated into nucleus and cytoplasm by either mass enucleation of cytochalasin-B-treated cells or by differential centrifugation of mechanically disrupted cells. Nuclei (karyoplasts) obtained by cytochalasin B treatment of cells contain more than ...