A simple and efficient method for chemical synthesis of lysophosphatidylethanolamine is described. 1-O-hexadecyl diazohydroxyacetone (A. K. Hajra, T. V. Saraswathi and A. K. Das. 1983. Chem. Phys. Lipids. 33: 179-193) was decomposed by benzyloxycarbonyl (CBZ) derivative of phosphorylethanolamine (I) to give 1-O-hexadecyl dihydroxyacetone-3-(N)-CBZ phosphorylethanolamine (II). Compound (II) was ...

Ceramides are sphingolipid second messengers that are involved in the mediation of cell death. There is accumulating evidence that mitochondria play a central role in ceramide-derived toxicity. We designed a novel cationic long-chain ceramide [omega-pyridinium bromide D-erythro-C16-ceramide (LCL-30)] targeting negatively charged mitochondria. Our results show that LCL-30 is highly cytotoxic to ...

This report describes the synthesis of an antibacterial material consisting of a gemini quaternary ammonium salt (gemini-QUAT) immobilized on ferrite powder, and its antibacterial activity. A gemini-QUAT containing two pyridinium residues per molecule, 4,4'-[1,3-(2,2-dihydroxylmethyl-1,3-dithiapropane)]bis (1-octylpyridinium bromide), was immobilized on ferrite powder by a reaction between the ...

Objectives . Alkylated derivatives of polyamines are able to block the growth cancer cells due their embedding into polyamine biosynthesis mechanisms. The study aimed synthesize lipophilic norspermine or triethylenetetramine based on formation a C–N bond during opening oxirane ring by primary amines expand number synthetic with antitumor activity. Methods starting compounds—glycidol alcoholate ...

The crystal structures of the title compounds, (3-aminOpyridiniUm),cU2cl6 and ( 3-aminopyridinium),Cu2Br6.H20, have been determined. The chloride dimer is monoclinic [a = 7.623 (1) A, b = 14.700 (2) A, c = 8.121 (1) A, j3 = 93.09 (1)O] and crystallizes in the space group PZ,/a, while the bromide dimer is monoclinic [a = 19.096 (5) A, 6 = 6.729 (1) A, c = 19.499 ( 5 ) A, /3 = 126.89 (1)O] and cr...

To reduce the shortcomings of existing filtering assistance, talc was modified by a two-step method. In first step, talcum powder heated microwave in acid solution. second stirred with Hexadecyl Trimethyl Ammonium Bromide (HTAB) solution for optimum time under an temperature. The temperature, and amount HTAB were investigated batch membrane filtration experiments kaolin suspension. effects new ...