Improvements in the two-step synthesis of 1,1,1,3,3,3-hexafluoro-2- (fluoromehoxy)propane (Sevoflurane) that result in the product cost reduction, safety level enhancement and positive environmental impacts are described. This process consists of chloromethylation reaction of 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) followed by a halogen-exchange fluorination. This is the first synthesis of Sev...

Improvements in the two-step synthesis of 1,1,1,3,3,3-hexafluoro-2- (fluoromehoxy)propane (Sevoflurane) that result in the product cost reduction, safety level enhancement and positive environmental impacts are described. This process consists of chloromethylation reaction of 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) followed by a halogen-exchange fluorination. This is the first synthesis of Sev...

According to the predominant theories, soluble amyloid-beta (Aβ) aggregates are the principal neurotoxic agents in Alzheimer's disease pathology, making them a popular target for the development of therapeutics and diagnostic markers. One of the most commonly used methods for determining the concentration of Aβ is ELISA. However, ELISA was developed for monomeric proteins and may be ill-suited ...

Kisspeptin 1 is a neuropeptide hormone of the RFamide family, which act as an upstream regulator of brain-pituitary-gonad (BPG) axis in most vertebrates including teleosts. In the present study, a 16 amino acid long putative mature bioactive peptide (kiss 1) from preprokisspeptin 1 of golden mahseer, Tor putitora (Hamilton, 1822), was synthesized and characterized using an integrated (experimen...

A good understanding of the limiting processes in rechargeable magnesium batteries is key to develop novel high-capacity/high-voltage cathode materials. Thereby, performance magnesium-ion can strongly depend on morphology intercalation cathode. Moreover, high mass loadings are essential for commercialization. In this work influence different studied addition impact particle size distribution ac...

The magnesium–sulfur (Mg-S) battery has attracted considerable attention as a candidate of post-lithium systems owing to its high volumetric energy density, safety, and cost effectiveness. However, the known shuttle effect soluble polysulfides during charge discharge leads rapid capacity fade hinders realization sulfur-based technology. Along with approaches for cathode design electrolyte formu...

improvements in the two-step synthesis of 1,1,1,3,3,3-hexafluoro-2- (fluoromehoxy)propane (sevoflurane) that result in the product cost reduction, safety level enhancement and positive environmental impacts are described. this process consists of chloromethylation reaction of 1,1,1,3,3,3-hexafluoro-2-propanol (hfip) followed by a halogen-exchange fluorination. this is the first synthesis of sev...