نتایج جستجو برای: higashi syndrome
تعداد نتایج: 622457 فیلتر نتایج به سال:
Proteins of the Chediak-Higashi/Beige (BEACH) family have been implicated in the function of lysosomes, as well as in signal transduction, but their molecular role is still poorly understood. In Dictyostelium, at least six members of the family can be identified. Here cells with mutations in two of these genes, LVSA and LVSB, were analyzed. Interestingly both mutants exhibited defects in the or...
A diminished chemotactic response was observed with the neutrophils of a patient with the Chediak-Higashi syndrome, who was not in the accelerated phase of the disease. An abnormally low release of myeloperoxidase from these cells during phagocytosis was also noted; this resulted in a decreased iodination capacity and probably also caused the defect in the intracellular killing of bacteria by t...
The anti-helminthic drug levamisole hydrochloride has been reported to stimulate immune responses in humans and experimental animals. We have investigated levamisole effects on human leukocyte locomotion in vitro in studies of neutrophils and mononuclear cells from normal adults, from patients with Chediak-Higashi disease and from patients with the syndrome of hyperimmunoglobulin E, recurrent p...
M. A. Avila,1 K. Suekuni,1 K. Umeo,2 H. Fukuoka,3 S. Yamanaka,3 and T. Takabatake1,4 1Department of Quantum Matter, ADSM, Hiroshima University, Higashi-Hiroshima 739-8530, Japan 2N-BARD, Hiroshima University, Higashi-Hiroshima 739-8526, Japan 3Department of Applied Chemistry, Graduate School of Engineering, Hiroshima University, Higashi-Hiroshima 739-8527, Japan 4Institute for Advanced Material...
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