Instituto do Coração (InCor) do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil. Correspondence to: Maria de Lourdes Higuchi, M.D., Laboratório de Anatomia Patológica, Instituto do Coração/InCor, Faculdade de Medicina da Universidade de São Paulo, Av. Dr. Enéas C. Aguiar 44, 05403-000 São Paulo, SP, Brasil. Tel: +55 11 30695252, FAX: +55 11 306...

Tomonari Shigemura, Kazunaga Agematsu, Takashi Yamazaki, Kazuo Sakashita, Yoshiko Nakayama, Yumiko Higuchi, Kazuyuki Matsuda and Kenichi Koike Department of Pediatrics, Department of Infection and Host Defense and Department of Laboratory Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan Accepted 7 March 2011 Correspondence to: Tomonari Shigemura, Department of Pediatric...

Dr. Higuchi is the leading figure in the real world applications of evolvable hardware. His speech will focus on semiconductor applications including analog LSI, clock timing adjustment, high-speed data transmission using the idea of evolvable hardware. While digital hardware design has made rapid progress due to advances in EDA software tools, analog hardware design is still highly reliant on ...

Title Gamma-polyglutamic acid-coated vectors for effective and safe gene therapy. Author(s) Kurosaki, Tomoaki; Kitahara, Takashi; Kawakami, Shigeru; Higuchi, Yuriko; Yamaguchi, Ayumi; Nakagawa, Hiroo; Kodama, Yukinobu; Hamamoto, Tomoyuki; Hashida, Mitsuru; Sasaki, Hitoshi Citation Journal of controlled release, 142(3), pp.404-410; 2010 Issue Date 2010-03-19 URL http://hdl.handle.net/10069/23096...

Using algorithms of Higuchi and of Grassberger and Procaccia, we study numerically how fractal dimensions cross over from finite-dimensional Brownian noise at short time scales to finite values of deterministic chaos at longer time scales for data generated from a Langevin equation that has a strange attractor in the limit of zero noise. Our results suggest that the crossover occurs at such sho...

purposes is a demanding task, especially to find recognition parameters for some consonants. In this paper, we show the initial analysis results of speech corpus, sampled with two sampling rates, 22050 and 8000 Hz, using Higuchi fractal dimension. The study shows that it might be possible to use fractal dimension value for classification of for example plosives /k/, /p/ and /t/. However, the an...

* contact author Human Genome Center, Institute of Medical Science, University of Tokyo 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan {imoto, takao, miyano}@ims.u-tokyo.ac.jp The Institute of Statistical Mathematics, 4-6-7, Minami-Azabu, Minato-ku, Tokyo, 106-8569, Japan [email protected] Graduate School of Genetic Resources Technology, Kyushu University 6-10-1 Hakozaki, Higashi-ku, Fuk...

Kumpei Tanisawa, Tomoko Ito, Xiaomin Sun, Ryuken Ise, Satomi Oshima, Zhen-Bo Cao, Shizuo Sakamoto, Masashi Tanaka, and Mitsuru Higuchi Graduate School of Sport Sciences, Waseda University, Tokorozawa, Saitama, Japan; Department of Genomics for Longevity and Health, Tokyo Metropolitan Institute of Gerontology, Itabashi, Tokyo, Japan; Faculty of Sport Sciences, Waseda University, Tokorozawa, Sait...

Human serum albumin nanoparticles (HSA-NPs) were synthesized using the modified desolvation method. Fourier transform infrared spectroscopy (FT-IR), electronic absorption spectroscopy (UV-Vis), Zeta Sizer as well as field emission scanning electron microscope (FE-SEM) of the sample confirmed the formation of HSA NPs with an average size of 68 nm. The obtained results shown that HSA-NPs was succ...

The aim of present work was to optimize the effect of Ethyl Cellulose (EC) and Polyvinyl Pyrrolidone (PVP) concentration in extended release solid dispersion of Glibenclamide using combination of hydrophilic and hydrophobic polymers such as Polyvinyl Pyrrolidone and Ethyl cellulose. The advantage of solid dispersion technique provides a unique approach to particle size reduction and increased r...