نتایج جستجو برای: histaminergic
تعداد نتایج: 669 فیلتر نتایج به سال:
The inflammatory mediators PGE2, DC-PGI2 and histamine as well as the beta-adrenergic drugs isoprenaline and salbutamol increase intracellular cyclic AMP-concentrations whereas Platelet Activating Factor does not induce any change in adenyl cyclase activity of normal human alveolar macrophages. Functional H2-histaminergic and beta 2-adrenergic receptor-subtypes are coupled to macrophage adenyl ...
BACKGROUND Central nervous system histaminergic tone is thought to play a role in appetite regulation. In animal models, histamine receptor 1 (HRH1) agonists and histamine receptor 3 (HRH3) antagonists decrease food intake. OBJECTIVE The objective of this study was to examine the acute effects of betahistine hydrochloride (an HRH1 agonist and HRH3 antagonist) on food intakes and appetites. ...
5. Finch, L., and P. E. Hicks. The cardiovascular effects of intraventricularly administered histamine in the anaesthetised rat. Naunyn Schmiedebergs Arch. Pharmacol. 293: 151–157, 1976. 6. Gatti, P. J., and S. B. Gertner. The effect of a vasopressin antagonist on the pressor response to histamine administered centrally. Neuropharmacology 22: 895–902, 1983. 7. Granata, A. R., N. Yoshinobu, M. K...
21 22 Itch of peripheral origin requires information transfer from the spinal cord to the brain for 23 perception. Here, primate spinothalamic tract (STT) neurons from lumbar spinal cord were 24 functionally characterized using in vivo electrophysiology to determine the role of these cells in 25 the transmission of pruriceptive information. 111 STT neurons were identified by antidromic 26 stimu...
The hypothesis that histaminergic neurons are involved in brain arousal is supported by many studies. However, the effects of the selective long-term abolition of histaminergic neurons on the sleep-wake cycle, indispensable in determining their functions, remain unknown. We have compared brain histamine(HA)-immunoreactivity and the cortical-EEG and sleep-wake cycle under baseline conditions or ...
Introduction. Histaminergic neurones are located in the tuberomammillary nucleus (TMN) of the posterior hypothalamus and project to most areas of the cerebral cortex, cerebellum, hypothalamus, and many brain stem nuclei (1,2). The central histaminergic neurones have important roles in the regulation of arousal, endrocrine and autonomic functions. The ascending histaminergic projection exerts a ...
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