Medicinal plants are effective in controlling plasma glucose level with minimal side effects and are commonly used in developing countries as an alternative therapy for the treatment of type 1 diabetes mellitus. The aim of this study is to evaluate the potential antidiabetic and antioxidant impacts of Balanites aegyptiaca and Petroselinum sativum extracts on streptozotocin-induced diabetic and ...

Background: Feed cost mainly constitutes 40-60% of total aquaculture production expenses, due to the inclusion expensive animal-derived ingredients feed industry. Studies suggested that herbivore and omnivore fish species can consume higher level carbohydrate (150–300 g/kg starch) as compared carnivore fish. However, lower utilization in fishes is less understood till date. In present work, It ...

Atropine is a non-selective muscarinic receptor antagonist. In overdoses, atropine is poisonous. It is sometimes added to potentially addictive drugs, particularly anti-diarrhoea opioid drugs such as diphenoxylate or difenoxin. The aim of this study was to investigate spatial memory and motor changes associated with varying doses (5 and 10 mg/kg body weight) ingestion of atropine, as well as it...

A study on the pituitary gland was carried out to record the histoarchitecture and occurrence of Herring bodies in 30 Madras red sheep. The tissues were processed for histological observations and were stained with standard histological and histochemical techniques. The neurohypophysis consisted of median eminence, infundibular stem, and infundibular process or pars nervosa in all the age group...

This study investigates the comparative hepatoprotective activity of crude ethanol extracts of Cuscuta australis against acetaminophen (APAP) intoxication. Thirty-six rats were randomly divided into six groups of 6 replicates: Group 1 which served as control received water. Group 2 was orally administered 835 mg/kg body wt. of paracetamol on day 8. Groups 3 and 4 were orally administered ethano...

An invasion model designed specifically for studying mechanisms of invasion of squamous-cell carcinomas was developed with murine buccal mucosa as the host tissue. The mucosal explants were destratified by growth in low-calcium medium (less than 0.07 mM), which results in a dorsal surface composed of one or two layers of basal epithelial cells. The explant has a three-dimensional histoarchitect...

Objective: The objective of the present study was to evaluate the acute and sub-acute toxicity profile of ethanolic extracts of Punica granatum (L).whole fruit (EPWF) and seeds (EPS) and synthetic ellagic acid (EA) in Swiss albino mice following OECD guidelines. Methods: In acute toxicity study, mice were orally administered 2000 mg/kg body weight of extracts and synthetic compound. In subacute...

The therapeutic potential of Cassia surattensis in reducing free radical-induced oxidative stress and inflammation particularly in hepatic diseases was evaluated in this study. The polyphenol rich C. surattensis seed extract showed good in vitro antioxidant. C. surattensis seed extract contained total phenolic content of 100.99 mg GAE/g dry weight and there was a positive correlation (r > 0.9) ...

OBJECTIVE This study evaluates hepatoprotective potential of Feronia limonia stem bark (FSB) extracts and fractions using experimental models. MATERIALS AND METHODS Activity levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) and cell viability were evaluated in HepG2 cells treated with carbon tetrachloride (CCl4) in presence or absence of FL extracts or fractions. A...