Clinical management of primary cutaneous melanomas is based on histopathological staging of the tumour. The aim of this study was to investigate, in a non-selected population in clinical practice, the agreement rate between general pathologists and pathologists experienced in melanoma in terms of the evaluation of histopathological prognostic parameters in cutaneous malignant melanomas, and to ...

The study of leprosy in children has indicated an incidence of 10% amongst leprosy patients attending the clinic. The duration of the disease was usually less than 2 years. The expression of leprosy in this group was either a macule and/or a plaque. Classification was, therefore, different and conforms to indeterminate (I), borderline tuberculoid (BT) and borderline (BB) leprosy. Only occasiona...

Objective: The aim of the study was to investigate the importance of consumption of the epidermis as an additional diagnostic criteria for malignant melanoma and to evaluate its relationship to clinicopathological findings. Material and Method: The age, gender, localization of the lesion and the histopathological parameters such as tumor type, Breslow thickness, ulceration, Clark’s level, mitos...

AIMS To formulate evidence based histopathological criteria for the diagnosis of acquired toxoplasmic lymphadenitis, in an area of high tuberculosis prevalence. METHODS Multiple histopathological parameters were assessed in a consecutive sample of biopsies from 68 patients presenting with lymphadenopathy with a duration of less than six months. Serum IgM enzyme linked immunosorbent assay was ...

The purpose of this study was to investigate the effects of royal jelly against radiation-induced oral mucositis in rats. This study was comprised of 48 adult male Sprague-Dawley rats, each between eight and 12 weeks old and weighing 275±35 g. These were divided randomly into six groups; Group C (control), Group IR (irradiation), Group IR+RJ50 (irradiation plus 50 mg/kg royal jelly), Group IR+R...

AIM To determine prognostic factors for recurrence of disease and tumour related mortality in patients with conjunctival melanoma. METHODS A retrospective analysis of clinical and histopathological data of 69 patients with histologically verified conjunctival melanoma. RESULTS As univariate analysis showed, significant risk factors for the development of recurrence were: irregular pigmentat...

The aim of the study was to estimate genetic alterations detected in ovarian cancer cells in correlation with other available parameters of histopathological and clinical character and to find important relations with impacts on the cancer prognosis. Additionally, we wanted to compare methods for evaluating genetic changes. Sixty patients with ovarian cancer were included in the study. The hist...

labeo rohita fingerlings were reared in freshwater and exposed to different concentrations of lead nitrate. after the exposure, one fish was sacrificed from each dose and the gill arches were removed. the ultrastructural changes on the gills of this cyprinid fish were investigated through scanning electron microscope (sem). lead treated gill tissues showed certain marked changes such as uplifti...

BACKGROUND/AIMS The identification of prognostic factors of metastatic development is one of the most important issues in colorectal cancer (CRC) research. The aim of this study was to determine the usefulness of colon tumor characteristics, including location, circumferential location, histological type, and histological grade, as predictors of metastases. MATERIALS AND METHODS To identify p...

BACKGROUND It is a well-established fact that in squamous cell carcinoma cases, the presence of lymph node metastases decreased the 5-year survival rate by 50% and also caused the recurrence of the primary tumor with development of distant metastases. Till date, the predictive factors for occult cervical lymph nodes metastases in cases of tongue squamous cell carcinoma remain inconclusive. Ther...