This chapter describe an overview of the clinical manifestations of CMV diseases that are in immunocompromised patients, including patients with human immunodeficiency virus infection / Acquired Immunodeficiency Syndrome (HIV / AIDS), organ transplant recipients, bone marrow transplant recipients, and individuals receiving immunosuppressive therapy or chemotherapeutic agents. We also present th...

Abstract Background Cryptococcal meningitis is an uncommon but serious infection with a high mortality and morbidity. Classically described in immunocompromised patients, including those solid organ transplants or HIV/AIDS, cryptococcosis has also been reported young otherwise healthy albeit rarely. Methods We retrospectively searched for all cases of cryptococcal (≤50 years) previously patient...

Invasive pulmonary aspergillosis (IPA) and pneumocystis jiroveci pneumonia (PCP) are life-threatening opportunistic infections that occur in immunocompromised hosts. Early diagnosis and treatment of these opportunistic infections is essential to the survival of immunocompromised patients. We report a 60-year-old man undergoing short-term steroid therapy after surgical resection of a brain tumor...

Opportunistic cytomegalovirus (CMV) infection is common in severely immunocompromised HIV-positive patients. The retina is the commonest site of involvement with hemorrhages a prominent feature. CMV retinitis affects 40% of HIV positive patients who have CD4 count of less than 100 cell/mm(3), and in these circumstances clinicians are likely to consider commencing anti-CMV therapy without consid...

Cryptococcosis is a life-threatening mycosis typically seen in immunocompromised patients. Pulmonary cryptococcosis generally presents as multiple or solitary nodular opacities. Cryptococcal infection presenting as a destructing cavernoma (cryptococcoma) without diffuse infiltration of the lung is an extremely rare presentation, even in immunocompromised patients. This report presents a healthy...

Penicilliosis is an infection caused by Penicillium marneffei, which is an opportunistic fungal pathogen endemic in areas such as Southeast Asia. It is usually found in patients infected with human immunodeficiency virus (HIV). P. marneffei is present in soil and is also associated with bamboo rats. Patients with AIDS are particularly susceptible to infection. Thus, penicilliosis is an importan...

A male intravenous drug abuser who was infected with hepatitis B and C, presented with a slowly progressive hemiplegia. Contrast enhanced computerized tomography of the head showed a solitary ring-enhanced mass with surrounding edema. Clinically brain tumor was suspected but a brain biopsy confirmed cerebral toxoplasmosis. An HIV test was not considered until the result of brain biopsy. He also...