Connectivity in the developing hippocampus displays a functional organization particularly effective in supporting network synchronization, as it includes superconnected hub neurons. We have previously shown that hub network function is supported by a subpopulation of GABA neurons. However, it is unclear whether hub cells are only transiently present or later develop into distinctive subclasses...

Hubs are special centers that used for switching, transferring and handling freight or passengers in transportation systems. The hub location problem deals with locating hub facilities and allocating demand nodes to hubs in order to route the traffic between origin–destination pairs. Aiming at minimizing the total costs, maximizing utilization of transporters, maximizing the service level, etc....

In the literature, hub-networks have often been modeled such as only one mode is considered for all transportation. Also, consolidated demand flows are assumed to be transferred directly between each origin-destination hub pairs. The previous assumptions impose restrictions on practical applications of hub-networks. fact, various transport modes usually retained freight transport, and intermoda...

Design of network, through which data, packages or even people can be transported, is an important issue for achieving a desired level of service quality at an acceptable cost. For this purpose, it is possible to design a network comprised of nodes that are connected to each other with dedicated lines. However, this kind of solution will not be cost effective. In order to decrease the total tra...

The stem cell niche provides a supportive microenvironment to maintain adult stem cells in their undifferentiated state. Adhesion between adult stem cells and niche cells or the local basement membrane ensures retention of stem cells in the niche environment. Drosophila male germline stem cells (GSCs) attach to somatic hub cells, a component of their niche, through E-cadherin-mediated adherens ...

In portable specially appointed systems (Manets), there is no altered foundation. A standout amongst the most broadly utilized directing conventions for a specially appointed system is the Ad hoc On Demand Distance Vector steering convention, shortened as AODV. In the customary AODV steering convention, source hub advances RREQ (Route Request) bundle to discover way to the terminus hub. The mod...

Although papillary renal cell carcinoma (PRCC) accounts for 10%-15% of renal cell carcinoma (RCC), no predictive molecular biomarker is currently applicable to guiding disease stage of PRCC patients. The mRNASeq data of PRCC and adjacent normal tissue in The Cancer Genome Atlas was analyzed to identify 1148 differentially expressed genes, on which weighted gene co-expression network analysis wa...