نتایج جستجو برای: human epidermal growth factor receptor

تعداد نتایج: 3136180  

Journal: :Japanese journal of clinical oncology 2010
Katsuhiro Masago Shiro Fujita Kaoru Irisa Yung Hak Kim Masataka Ichikawa Tadashi Mio Michiaki Mishima

Recently, two small-molecule kinase inhibitors targeting epidermal growth factor receptor have proven effective in the treatment of non-small cell lung cancer. There are specific activating mutations within the tyrosine kinase domain of epidermal growth factor receptor related to the sensitivity of tyrosine kinase inhibitors. However, it is unknown whether rare mutations in the N-lobe (exons 18...

2017
Gaye Güler Tezel Ebru Şener Çisel Aydın Sevgen Önder

AIMS Epidermal growth factor receptor mutation analysis in non-small cell lung cancer is important for selecting patients who will receive treatment with tyrosine kinase inhibitors. In this study, we aimed to investigate the prevalence of epidermal growth factor receptor mutations and mutation patterns in the Turkish population. METHODS We retrospectively reviewed molecular pathology reports ...

2016
Ganesh Adhikari

ABSTRSCT: The advent of human epidermal growth factor receptor-2 (HER2) Status and biomarker testing has modified the treatment and prognosis of gastric, breast and colorectal cancer. Epidermal growth factor receptor and HER-2 family maneuvers a key role in the exploitation of gastric cancer by detecting the epidermis express in gastric cancer tissue and to investigate serum and tissue HER2. Ta...

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