in this research, the magnetite nanoparticles (fe304) were prepared by coprecipitation of fe3+ andfe solution in alkaline medium. two kinds of surfactants, cetyl tri methyl ammonium bromide(ctab) and cetyl pyridinum chloride (cpc) were used in the synthesis. fe304 nanoparticles werecoated with human serum albumin (hsa) and bovine serum albumin (bsa). characteristics ofcoated magnetic nanopartic...

BACKGROUND The authors investigated the effect of a single preoperative bolus of erythropoietin on perioperative transfusion requirement and erythropoiesis in patients with preoperative anemia undergoing valvular heart surgery. METHODS In this prospective, single-site, single-blinded, randomized, and parallel-arm controlled trial, 74 patients with preoperative anemia were randomly allocated t...

Although iron has been known to be indispensable for the formation of chlorophyll (11), the mechanism for the iron requirement has not been identified at the level of a chemical or enzymic reaction. We report here experiments on the possible involvement of iron in porphyrin metabolism. Pappenheimer (16) found that porphyrins were produced by iron-deficient Corynebacterium diphtheriae. Similarly...

The aerobic gram negative bacterium Pseudomonas aeruginosa is an opportunistic pathogen responsible for life threatening acute and chronic infections in humans. As part of chronic infection P. aeruginosa forms biofilms, which shield the encased bacteria from host immune clearance and provide an impermeable and protective barrier against currently available antimicrobial agents. P. aeruginosa ha...

Adequate acclimatization time to enable adjustment to hypoxic conditions is one of the most important aspects for mountaineers ascending to high altitude. Accordingly, most reviews emphasize mechanisms that cope with reduced oxygen supply. However, during sojourns to high altitude adjustment to elevated iron demand is equally critical. Thus in this review we focus on the interaction between oxy...