BACKGROUND AND OBJECTIVE Cellular immunity abnormalities are associated with sarcoidosis. Normal cellular immunity is required for adequate humoral immunity; therefore, a decreased humoral immune response is possible in patients with sarcoidosis. We evaluated humoral immunity by vaccinating patients with sarcoidosis against tetanus. PATIENTS AND METHOD We screened 60 patients with sarcoidosis...

While antibody titers and neutralization are considered the gold standard for the selection of successful vaccines, these parameters are often inadequate predictors of protective immunity. As antibodies mediate an array of extra-neutralizing Fc functions, when neutralization fails to predict protection, investigating Fc-mediated activity may help identify immunological correlates and mechanism(...

At the present time, studying humoral immunity to new coronavirus infection is among most important tasks. The COVID-19 induces a protective pool of specific antibodies determining severity and duration such immune protection after convalescence. antibody testing also necessary for assessing efficiency anti-COVID vaccines in order defeat SARS-CoV-2 pandemic. Despite enormous interest scientific...