To the Editor of the " Indian Medical Gazette." Silt, -My remarks 011 the above subject, to which Dr. Daniels takes exception in your November issue, did not refer to his own! valuable papers, but to private conversations with Mr. Hutchinson and others. I had noted that Dr. Daniels' statements referred to the aboriginal Fijians only. My septicism applied to tho moro sweeping statement that syph...

Meena Ramchandani, MD, MPH; Ronnie Russell; Lichen Jing, PhD; Amalia Magaret, PhD; Stacy Selke, MS; Meei-Li Huang, PhD; Eric Strachan, PhD; Anna Wald, MD, MPH, FIDSA; David M. Koelle, MD; Infectious Disease, University of Washington, Seattle, WA; University of Washington, Seattle, WA; Department of Laboratory Medicine, University of Washington, Seattle, WA; Laboratory Medicine, University of Wa...

F a c u l t y M e n t o r Tara C. Hutchinson Henry Samueli School of Engineering

IN this issue of the Journal, I have included a summary of a workshop held in November 2007 on the topic of Hutchinson-Gilford Progeria Syndrome (HGPS) (1). This syndrome was first described over 120 years ago by Hutchinson (2), and although the phenotype does include some aging-like changes, biogerontologists have questioned whether it is a viable model for studying accelerated aging (3). The ...

WHEREABOUTS UNCERTAIN JOHN HUTCHNSON, described as "surgeon", was one of seven cabin passengers who left London in September 18521 on the first Australian voyage of the Washington Irving (900 tons, Captain John Jones).2 The voyage was recorded as "without untoward incidents and very pleasant" although one of approximately 270 intermediate and steerage passengers (including about fifty children)...

John Hutchinson, as governor of Nottingham and its castle, was crucial to parliament’s cause in the north east Midlands during first civil war. Alongside Sir Gell, Hutchinson’s counterpart Derbyshire he largely responsible for initial establishment parliamentarian presence region. Throughout war, despite sporadic isolation, castle provided an anchor rendezvous parliament However, there are ques...

The Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic disease characterized by an accelerated aging, due to the accumulation in nucleus of a toxic protein called progerin, leading to abnormal gene expression and potential microRNA (miRNA) deregulation. To evaluate the role of miRNAs in HGPS, we conducted an in vitro miRNome analysis by RT-qPCR on dermal fibroblasts of 5 patients and...