in this study, a hybrid intelligent model has been designed to predict groundwater inflow to a mine pit during its advance. novel hybrid method coupling artificial neural network (ann) with genetic algorithm (ga) called ann-ga, was utilised. ratios of pit depth to aquifer thickness, pit bottom radius to its top radius, inverse of pit advance time and the hydraulic head (hh) in the observation w...

Interspecific hybrid embryos are useful models for the study of maternal-fetal interactions, transmission pattern of species-specific markers and parental contributions to growth and developmental potential of pre-attachment embryos. In an attempt to investigate the possibility of producing hybrid embryos of domestic cattle (Bos taurus) and water buffalo (Bubalus bubalis), cattle oocytes were e...

A formal synthesis of the antiviral drug (-)-oseltamivir (Tamiflu) has been accomplished starting from m-anisic acid via a dissolving metal or electrochemical Birch reduction. The correct absolute stereochemistry is efficiently set through enzyme-catalyzed carbonyl reduction on resultant racemic α,β-unsaturated ketone. screen broad ketoreductase (KRED) library identified several that deliver de...

This study examines ICT’s impact in meeting the challenges, Chinese tobacco companies are facing in the context of an open door policy as well as the WTO entry. The analysis is based on an in-depth study of the ICT evolution in Chinese tobacco companies. For our conclusion we use Nolan’s stage hypothesis and the strategic grid model. We show that, depending on a company’s strategic grid cell, d...

To study the water entry ballistic trajectory of a torpedo, the wind tunnel experiment has been done based on the similarity principle. Then the drag coefficient of the torpedo is got when it enters the water, which is amended by the introduction of continuous supercavitation factor and local cavity effect factor. The vertical plane motion equations are established to get the torpedo’s trajecto...

OBJECTIVE To provide clinically meaningful, normative reference data that describe the timing of sexual maturity indicators among a national sample of US children and to determine the degree of racial/ethnic differences in these estimates for each maturity indicator. METHODS Tanner staging assessment of sexual maturity indicators was recorded from 4263 non-Hispanic white, black, and Mexican A...

This paper presents the results of an experimental study of endogenous entry and bidding behavior in ...rst-price independent private value auctions. In the ...rst stage N potential bidders simultaneously decide whether to participate in an auction or to claim a ...xed outside option. At this stage all potential bidders know N, the distribution of possible values, and the value of the outside o...

Normal rat kidney (NRK) fibroblasts have electrophysiological properties and intracellular calcium dynamics that are dependent upon their growth stage. In the present study we show that this differential behavior coincides with a differential calcium entry that can be either capacitative or non-capacitative. Confluent cells made quiescent by serum deprivation, which have a stable membrane poten...