Chemical functionalization of cellulose aims to adjust the properties of macromolecule for different purposes, particularly, as a chemical feedstock for production of cellulose derivatives for a variety of applications. The conventional sources of cellulose include cotton linters and wood pulp which now-a-days are discouraged on account of the cost of the former and environment conservative reg...

In majority of individuals blood pressure rises in the early morning hours, which lead to serious cardiovascular complications. Formulation of pulsatile system makes it possible to deliver drug at definite period of time when symptoms of the disease condition are most critical. The purpose of the present work was to develop pulsatile release tablet of losartan potassium for chronotherapy in hyp...

Lamotrigine is a substituted asymmetric triazine. It is a white to pale cream-coloured powder. It is slightly soluble in ethanol and chloroform, and very slightly soluble in water. The pKa of lamotrigine at 25°C is 5.7. Each Lamictal Dispersible/Chewable tablet also contains calcium carbonate, hydroxypropyl cellulose, aluminium magnesium silicate, sodium starch glycollate, povidone, saccharin s...

*e-mail: [email protected]; [email protected] Present addresses: Fundação Estadual de Proteção Ambiental Henrique Luis Roessler, Rua Carlos Chagas, 55, 90030-020 Porto Alegre-RS, Brazil and Universidade Estadual do Rio Grande do Sul, Unidade Bento Gonçalves, Av. Benjamin Constant, 229, 95700-000 Bento Gonçalves-RS, Brazil. Anionic Surfactant Aggregation with (Hydroxypropyl)cellulose i...

As final attributes of dosage form largely depend on the properties excipients used, understanding effect physicochemical is important. In present study, six grades L-HPC with varying degrees particle size and hydroxypropyl content influence grade compaction as well disintegration behavior were studied. All compressed at different compression loads to achieve tablet porosity. Compressibility co...

Terbinafine hydrochloride is a white to off-white fine crystalline powder. It is freely soluble in methanol and methylene chloride, soluble in ethanol, and slightly soluble in water. Each tablet contains: Active Ingredients: terbinafine hydrochloride (equivalent to 250 mg base) Inactive Ingredients: colloidal silicon dioxide, NF; hydroxypropyl methylcellulose, USP; magnesium stearate, NF; micro...

ABSTRACT
 In 2020 the number of cases Dengue Hemorrhagic Fever in Indonesia until 49th week reached 95,893 and caused death around 661 people. This study aims to obtain bestformula buccal film by optimizing concentration HPMC K15M Na. CMC evaluation characterization ofpreparations with 3 variations ratios against formulas on Na polymer excipients. include F1 0.67% : 0.33% ; F2 0.65% 0.5% F...

Particle electrification is a common phenomenon that occurs in many powder handling industries such as pharmaceuticals and detergents etc. The unit operations involved in the manufacture of pharmaceutical formulations frequently subject particles to frictional sliding and impact against processing surfaces, giving rise to tribo-electric charging. Pharmaceutical materials, in particular, are sus...

In this work polyaniline nanocomposites were synthesized in aqueous media by using ammonium proxy disulfat (APS) (10g/l) as an oxidant in the presence of hydroxy propyl cellulose (HPC) (2,5,10 g/l) as a surfactant, poly (vinyl chloride) (10,30 g/l) as an additive and sulfuric acid (H2SO4). The effects of concentration of surfactant and additive on morphology have been ...