We describe a patient with inherited plasminogen deficiency who developed extensive cerebral venous thrombosis. Several other conditions that might have contributed to a hypercoagulable state, including mild thrombocytosis, thyrotoxicosis, and a chronic inflammatory lung disorder, were present. We also discuss the evidence linking plasminogen deficiency with a thrombophilic state. The diagnosis...

BrMedJ 1990;300:590-2 Portal vein thrombosis may be the first presentation of a hypercoagulable state. We report a case that illustrates a diagnostic approach to show the extent of the splanchnic venous thrombus and to investigate its haematological aetiology. The discussion focused on the association between portal vein thrombosis and myeloproliferative disease and controversies in managing th...

The association of lymphoid neoplasms and antiphospolipid antibodies (APA), with or without thromboembolic complications, has been reported in several cases. We describe one case of B-cell non-Hodgkinís lymphoma (NHL) in which the combination of rituximab with standard chemotherapy led to the complete remission of a severe hypercoagulable state associated with APA.

Uterine adenomyosis, which is known as a benign gynecological disease, can induce hypercoagulable state and be an uncommon cause of cerebral thromboembolism, infarction common in patients with malignant neoplasm. We report woman uterine adenomyosis who shows several episodes discuss the stoke mechanism treatment this under-recognized etiology stroke.

conclusions if seizure occurs during the peripartum period, along with providing complete cardiovascular and respiratory support, advanced diagnostic measures are needed and cerebral venous sinus thrombosis should be considered as a possible diagnosis. introduction seizure involves less than 1% of pregnancies; however it is associated with increased maternal and fetal complications. cerebral ve...

Deep vein thrombosis (DVT) in children is usually associated with inherited or acquired hypercoagulable state, mechanical obstruction, fractures of long bones, central venous catheterization and prolonged immobility. We report DVT in 4 children with culture proven staphylococcal septicemia. One child died, while other three survived with appropriate antibiotics and anticoagulation therapy.

History of adverse outcomes justifies screening Page 59 T hrombophilia has been widely investigated—and that may be one of the main challenges in detecting and managing it during pregnancy: Numerous studies have yielded different estimates of the incidence of various clotting disorders in pregnancy—itself a hypercoagulable state— and conflicting screening and prevention recommendations. The aut...

Mycoplasma pneumoniae, commonly known as a major causative agent of primary atypical pneumonia, also causes various kinds of extrapulmonary manifestations involving almost all the organs of the human body. The author has classified the extrapulmonary manifestations due to M. pneumoniae infection into three categories: the first is a direct type in which locally induced cytokines play a role, th...

Acute myocardial infarction is a rare condition in young athletes. One of the causes could be a hypercoagulable state due to congenital antithrombin III deficiency, together with a prothrombotic state soon after strenuous physical training. We present the case of myocardial reinfarction in young football player with antithrombin III deficiency, treated with primary percutaneous coronary interve...

Thromboelastography (TEG) using disposable plastic cups and pins was performed with native whole blood (native group) in 17 nonpregnant volunteers, 134 healthy term pregnant women (>36 wk gestation), and 69 postpartum women. Thromboelastography was also performed with celite-activated whole blood (celite group) in 15 nonpregnant female volunteers, 38 healthy term pregnant women, and 34 postpart...