نتایج جستجو برای: hypocitraturia
تعداد نتایج: 115 فیلتر نتایج به سال:
Renal tubular acidosis are forms of metabolic acidosis characterized by an impairment of urinary acidification due to a lack of urine excretion of protons or loss of bicarbonates. Primary distal renal acidosis (dRTA) is characterized by hyperchloremic metabolic acidosis due to failure in proton excretion, variably severe nephrocalcinosis and/or nephrolithiasis associated with hypercalciuria and...
Background: Urolithiasis is already one of the oldest diseases even in pediatric patients. The prevalence of kidney stones is estimated to be 1:20.000 children/year. The medium age of onset is between 5-7 years. The aim of our study was to see the characteristic features, predisposing factors and therapeutic procedures for urolithiasis in children, as well as metabolic abnormalities especially ...
OBJECTIVE To obtain regional reference values for calcium, uric acid and citrate urinary excretion and establish a correlation between those excretions in 24-hour urine sample and single urine sample for their use in clinical practice. METHODS A hundred and twenty-five healthy children and adolescents were randomly chosen and submitted to the following protocol: clinical examination, biochemi...
The metabolism of Krebs cycle intermediates is of fundamental importance for eukaryotic cells. In the kidney, these intermediates are transported actively into epithelial cells. Because citrate is a potent inhibitor for calcium stone formation, excessive uptake results in nephrolithiasis due to hypocitraturia. We report the cloning and characterization of a rat kidney dicarboxylate transporter ...
BACKGROUND Metabolic evaluation in recurrent idiopathic calcium renal stone-formers (RCSF) was analysed with respect to the following questions: (1) do three 24-h urines provide more diagnostic accuracy in the metabolic evaluation of RCSF than 1 or 2 urines?; (2) does time after stone event influence the diagnostic yield?; (3) is urine composition at weekends different from that at mid-week?; (...
A 46 year old man was referred to hospital by his general practitioner with abnormal bone biochemistry. He had presented with poor appetite, fatigue, myalgia, and backache. Serum calcium, corrected for albumin, was 2.63 mmol/litre (reference range, 2.12–2.62), serum phosphate was 0.85 mmol/litre (normal range, 0.7–1.4), and alkaline phos-phatase was 367 IU/litre (normal range, 80–280). There wa...
In 222 random spot urine specimens, the calcium concentration and calcium oxalate saturation [DG(CaOx)] were significantly higher among stone formers than among non-stone formers, while the citrate and creatinine-corrected citrate concentrations were lower. In 188 24-hour urine specimens, magnesium excretion was lower among stone formers than non-stone formers, while the creatinine-corrected ca...
OBJECTIVE Diet interventions may reduce the risk of urinary stone formation and its recurrence, but there is no conclusive consensus in the literature regarding the effectiveness of dietary interventions and recommendations about specific diets for patients with urinary calculi. The aim of this study was to review the studies reporting the effects of different dietary interventions for the modi...
nors underwent evaluation at our center between February 2002 and May 2005 that included renal imaging. Seventy-six were eventually excluded for medical or surgical reasons. Out of those excluded, eight were found to have one or more kidney stones by ultrasound (two patients) or computed tomography (CT) scan (six patients). No patient gave a previous history of hypertension, nephrolithiasis or ...
Dear Editor, Nephrolithiasis is a common urinary problem with a worldwide estimated prevalence rate of 4–20% and a 5-year recurrence rate of 50%. It accounts for significant expense and morbidity. Recurrent stone disease is a major cause of end-stage renal disease, which may eventually lead to renal transplantation. The prevalence rate of stone disease, in the Middle East region and in Iran, is...
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