Since ancient times, plants have been an exemplary source of medicine. Ayurveda and other Indian literature mentioned the use of plants in treatment of various human ailments. Medical plants play an important role in the management of diabetes mellitus especially in developing countries where resources are meager. Oral hypoglycemic agents like sulphonylureas and biguanides are still the major p...

Diabetes mellitus is known as metabolic disorder related to glucose intolerance which is characterized by hyperglycemia. Diabetes mellitus can be treated by insulin and oral hypoglycemic agents. Most of known oral hypoglycemic are peroxisome proliferatoractivated receptors (PPAR) agonist. There are three different subtypes of PPARs are identified and they are involved in glucose metabolism. A b...

Hypoglycemic, diuretic and hypocholesterolemic effects of roots of W. somnifera (ashvagandha) were assessed on human subjects. Six mild NIDDM subjects and six mild hypercholesterolemic subjects were treated with the powder of roots of W. somnifera for 30 days. Suitable parameters were studied in the blood and urine samples of the subjects along with dietary pattern before and at the end of trea...

A 73-year-old diabetic man treated with oral hypoglycemic agents presented with dysarthia. He was alert and could obey simple verbal and written commands. His dysarthria was too severe to understand. Muscle tone of his legs was increased. Deep tendon reflexes were generally decreased without pathological reflex or clonus. The blood glucose level was 44 mg/dL. Diffusion-weighted MR imaging (DWI)...