High fructose feeding in rats induces insulin resistance, hyperinsulinemia, hyperglycemia and dyslipidemia. The present study was undertaken to determine the hypolipidemic effect of food seasoning spices mixture on fructose-fed insulin resistant rats. Male Wistar rats received a daily diet containing either 60% fructose or 60% starch. They were administered with the spices mixture at three diff...

The present study was designed to investigate the hypolipidemic effect of ethanolic extract from whole plant of Lactuca runcinata (DC.) in rats fed with atherogenic diet (AD). The acute toxicity study shows that the ethanolic extract are safe up to 2000 mg/kg, thus one tenth of this dose was consider as evaluation dose. Ethanolic extract of Lactuca runcinata was administered in doses of 200 and...

two proprotein convertase subtilisin/kexin type 9 (PcsK9) inhibitors, evolocumab and alirocumab, have recently been approved by both the food and drug Administration (fdA) and the european Medicines Agency (eMA) for the treatment of hypercholesterolemia. these fully human monoclonal antibodies selectively block PcsK9, thus permitting the low-density lipoprotein (LdL) receptor to effectively rec...

Maslinic acid is a pentacyclic triterpenoid acid. Recent research has shown that it various biological activities such as anti-tumor, hypoglycaemic and hypolipidemic. Among them, the hypolipidemic effect prominent this study aims to further explore its mechanism of action in treatment hyperlipidemia. The chemical structure maslinic was obtained from PubChem. Based on structure, bioavailability ...

objective: turmeric (curcuma longa linn) is a medicinal plant that contains curcumin. there is a growing interest in using curcumin powder (cp) as feed additives for antioxidative and antimicrobial properties to improve human health. this study was conducted to determine the appropriate levels of cp on blood parameters, immunity, and histology of jejunum in hens. materials and methods: a total ...

background: hyperlipidemia is a heterogeneous group of disorders characterized by an excess of lipids in the bloodstream objective: given previous studies on barberry and melissa officinalis extracts, this study aims at comparing hypolipidemic activities of melissa officinalis extract and berberis vulgaris. methods: for the purpose of this study, 64 wistar rats were selected and divided into 8 ...