We propose and study a new method, called the Interior Epigraph Directions (IED) method, for solving constrained nonsmooth and nonconvex optimization. The IED method considers the dual problem induced by a generalized augmented Lagrangian duality scheme, and obtains the primal solution by generating a sequence of iterates in the interior of the dual epigraph. First, a deflected subgradient (DSG...

Till now, most studies of the Blood Oxygen Level-Dependent (BOLD) response to interictal epileptic discharges (IED) have assumed that its time course matches closely to that of brief physiological stimuli, commonly called the canonical event-related haemodynamic response function (canonical HRF). Analyses based on that assumption have produced significant response patterns that are generally co...

PURPOSE To assess the latency of interictal epileptiform discharges (IED) and seizures in long-term EEG recordings of patients with epilepsy. METHOD IED latency was measured in 210 consecutive patients (mean (SD) age 38.6 ± 13.9 years) with active epilepsy and the relationship to clinical variables was analyzed retrospectively. Median duration of EEG recording was 101.5h (95% confidence inter...

The objective of this study was to determine if platelet 5-HT transporter (5-HTT) sites vary as a function of aggression, and/or impulsiveness, and differ as a function of Intermittent Explosive Disorder (IED). Accordingly, the number of platelet 5-HTT sites was assessed in 100 personality disordered (PD) individuals with varying degrees of aggressiveness. The number of platelet 5-HTT sites was...

PURPOSE We examined whether early EEG changes in a 24-h EEG at 6 weeks of treatment were related to the later clinical response to the ketogenic diet (KD) in a 6-month period of treatment. METHODS We examined 34 patients with heterogeneous epilepsy syndromes (21 children, 13 adults) and found 9 clinical responders (≥50% seizure reduction); this is a responder rate of 26%. We visually counted ...

We prove that the set of orthogonal separable coordinates on an arbitrary (pseudo-)Riemannian manifold carries a natural structure of a projective variety, equipped with an action of the isometry group. This leads us to propose a new, algebraic geometric approach to the classification of orthogonal separable coordinates by studying the structure of this variety. We give an example where this ap...

This article describes a theory that uses mental models to integrate deductive, inductive, and probabilistic reasoning. It spells out the main principles of the theory and illustrates them with examples from various domains. It shows how models underlie inductions, explanations, estimates of probabilities, and informal algorithms. In all these cases, a central principle is that the mind represe...

Indicadores educacionais são importantes para a gestão, uma vez que representam estatísticas de características mensuráveis das escolas, permitindo obtenção um perfil suas condições. Objetivou-se com este trabalho analisar e discutir as correlações existentes entre os indicadores educacionais: percentual docentes curso superior (DSU), adequação da formação docente (AFD), esforço (IED) nível soc...

This paper presents a fuzzy approach to the identification of organizational values and culture. The proposed approach has been developed from crisp assessment methods in the literature and has been applied to the Industrial Engineering Department (IED) at a state university in Turkey. Highly subjective judgments and ambiguity regarding the presence of values and the culture type of the organiz...

We developed an International Electrotechnical Commission (IEC) 61850-based centralized protection scheme to prevent single line-to-ground (SLG) faults in the feeders and busbars of ungrounded distribution systems. Each feeder intelligent electronic device (IED) measures its zero-sequence current voltage signals periodically transmits phasors a central IED via Generic Oriented Object Substation...