nloaded kel cell polyomavirus (MCPyV) is a common infectious agent that is likely involved in the etiology st Merkel cell carcinomas (MCC). Serum antibodies recognizing the MCPyV capsid protein VP1 are able at high titer in nearly all MCC patients and remain stable over time. Although antibodies to the apsid indicate prior MCPyV infection, they provide limited clinical insight into MCC because ...

Merkel cell polyomavirus (MCPyV) is a common infectious agent that is likely involved in the etiology of most Merkel cell carcinomas (MCC). Serum antibodies recognizing the MCPyV capsid protein VP1 are detectable at high titer in nearly all MCC patients and remain stable over time. Although antibodies to the viral capsid indicate prior MCPyV infection, they provide limited clinical insight into...

BACKGROUND Production of antibodies that are specific for allergens is an important pathological process in inflammatory allergic diseases. These contain the antibodies against antigens of Candida albicans, one of the normal microbial flora in an intestinal tract. We studied the effects of the prednisolone administration on the production of anti-Candida antibodies in the gastrointestinally C. ...

According to the WHO Strategic Plan, measles should be eradicated in 2020 five Regions including European Region. However, large outbreaks are being periodically registered diverse countries. In Republic of Serbia (SRB), 5,076 cases were detected 2018, among which 15 fatal. Aim study was examine herd immunity and rubella viruses population Serbia. Materials methods . Blood serum samples obtaine...

OBJECTIVE To characterize the prevalence and clinical correlates of anti-troponin I antibodies in renal transplant patients. METHODS A group of 48 consecutive renal transplant patients under immunosuppressive therapy were studied. Anti-troponin I antibodies were measured and clinical data were retrieved. RESULTS An anti-troponin I antibody titer <1:40 was seen in most patients (30). IgG ant...

PURPOSE Chlamydia Pneumoniae has been shown to be associated with atherosclerosis, myocardial infarction, and abdominal aortic aneurysms (AAAs). The possible association between AAA expansion and C pneumoniae infection was therefore assessed. METHODS Blood samples were taken from patients with an AAA that was considered for surgical repair after having been diagnosed by means of the Chicheste...

Antimitochondrial antibodies (AMAs) are the classic serologic marker in primary biliary cirrhosis (PBC). However, there have been only limited attempts to study changes in titer or isotype analysis of such AMAs in patients followed for long periods of time. We took advantage of stored sera from well-characterized patients with PBC followed for a period of 7-28 years (mean duration of 13.5 years...

The cell surface gangliosides GM2, GD2, and GD3 are often overexpressed in malignant melanoma. We have shown previously that immunization of melanoma patients with GM2 and Bacillus Calmette-Guérin induced an IgM antibody response in most patients and that patients with high titer GM2 antibodies showed increased survival. As is commonly seen with carbohydrate antigens (which are T independent), ...

A serologic test for antibodies is useful for diagnosis of Helicobacter pylori(H.pylori) infection in children. We evaluated the reliability of H.pylori IgG antibody titer in grading the severity of infection in children. We surveyed the sero-prevalence of H.pylori infection in 300 healthy school children (13 to 15 years old). Thirty-four percent(102 of 300 children) were sero-positive for H.py...

Fulminant hepatitis by Epstein-Barr virus is a rare event which is predominantly due to primary infection. We report a rare case of fatal hepatic failure due to Epstein-Barr virus reactivation in a 19-year-old boy who was taking oral steroids. Transaminase peak and the fulminant course of the disease began soon after steroid interruption. Epstein-Barr virus reactivation was diagnosed on the bas...