The development of platforms able of handling transparently distribution, heterogeneity and multi-language software in the framework of an object model has been perceived as a promising direction to develop distributed applications. We wanted to develop a platform in which programmers of distributed applications could beneet from a coherent and uniform object model, as in traditional OO languag...

NMR experiments at very low temperatures have been carried out for a long time, generally not as a general purpose method for analyzing structure and dynamics but rather as a convenient diagnostic tool in the study of substances whose special properties at very low temperatures are of interest. These include most prominently solid hydrogen and solid and liquid helium-3. It must always have been...

In this study, we attempted to identify and assess effects of isoegomaketone (IK) isolated from Perilla frutescens var. crispa on the development of rheumatoid arthritis (RA). RA was induced in male Balb/c mice by collagen antibody injection. Experimental animals were randomly divided into five groups: normal, collagen antibody-induced arthritis (CAIA), CAIA + IK (5 mg/kg/day), CAIA + IK (10 mg...

The distinction between indigenous and Western/scientific knowledge can present problems for those who believe in the significance of indigenous knowledge for development. This article examines some of the contradictions and ironies involved in accenting the importance of indigenous knowledge, with a view to eliciting a dialogue on the subject. The last part of the article tentatively explores ...

a. N1 = {(i1, i2, . . . , in) : ik ∈ Ik for all k ∈ {1, 2, . . . , n}} and b. N2 = {(x1, x2, . . . , xn) : ∑n k=1 xk = 0}. Proof. To prove (a), it suffices to show, by Proposition 1, that N1 is nonempty and x + ry ∈ N1 for all r ∈ R and all x, y ∈ N1. For the first condition, (0, 0, . . . , 0) ∈ N1 since Ik is a subgroup of R containing the additive identity 0 for all k ∈ {1, 2, . . . , n}. Tha...

The progenitor cells from the anterior part of the neonatal subventricular zone, the SVZa, are unusual in that, although they undergo division, they have a neuronal phenotype. To characterize the electrophysiological properties of the SVZa precursor cells, recordings were made of potassium and sodium currents from SVZa cells that were removed from postnatal day 0-1 rats and cultured for 1 day. ...

In addition to increasing the conductance to sodium, light reduces the maintained voltage-dependent potassium current (iK) in Limulus ventral photoreceptors. We have investigated the mechanism underlying this long-lasting decrease in ik. Intracellular injection of calcium produced a similar reduction of the voltage-dependent outward current. This reduction was not due to an activation of the vo...

Block of the delayed rectifier potassium current, IK, by the class IC antiarrhythmic agent, flecainide, and by the novel selective class III antiarrhythmic agent, E-4031, were compared in isolated cat ventricular myocytes using the single suction-pipette, voltage-clamp technique. Flecainide (10 microM) markedly reduced IK elicited on depolarization steps to plateau voltages (+10 mV) and nearly ...