نتایج جستجو برای: il 13
تعداد نتایج: 462785 فیلتر نتایج به سال:
Introduction:To evaluate the role of allergic-type and infectious-type cytokines in children with chronic otitis media with effusion (OME) Materials and Methods:We investigated serum levels of interleukins (IL)-4, IL-5, and IL-13, along with interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α), by enzyme-linked immunosorbent assay (ELISA) in 35 children with OME and 28 healthy contr...
Tralokinumab, a fully human monoclonal antibody specifically targeting the IL-13 cytokine, has demonstrated clinical efficacy and safety in patients with moderate-to-severe atopic dermatitis. Tralokinumab binds high affinity which prevents interaction of IL-13Rα1 subsequent signaling. Similarly, tralokinumab-bound cannot bind to IL-13Rα2, proposed decoy receptor is reported extraordinarily affi...
Intratracheal injection of FITC results in acute lung injury and progresses to fibrosis by day 21 postchallenge. In response to FITC, BALB/c mice produce IL-4 and IL-13 in the lung. To investigate whether IL-4 and/or IL-13 were important profibrotic mediators in this model, we examined the fibrotic response to FITC in mice that were genetically deficient in IL-4 (IL-4(-/-)), IL-13 (IL-13(-/-)),...
The heterogeneous etiology of asthma makes its diagnosis complicated. Measurement cytokine levels could be relevant in determining the phenotype, predicting severity, and identifying treatment type. Enzyme-linked immunosorbent assay (ELISA) is one most reliable methods, with high sensitivity specificity. This study aimed to determine accuracy utility interleukin (IL)-13 IL-17 A diagnosing child...
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