نتایج جستجو برای: il 17
تعداد نتایج: 402546 فیلتر نتایج به سال:
background: il-4 is a cytokine that induces differentiation of naive helper t cells into th2 cells. once activated by il-4, th2 cells subsequently produce additional il-4. objective: to examine the effect of il-4 on il-17 production and its effect in collagen- induced arthritis (cia) mice. method: in this study, a chicken collagen-ii-induced experimental arthritis (cia) model was used in dba/1 ...
T-helper 17 (Th17) cells are characterized by producing interleukin-17 (IL-17, also called IL-17A), IL-17F, IL-21, and IL-22 and potentially TNF- α and IL-6 upon certain stimulation. IL-23, which promotes Th17 cell development, as well as IL-17 and IL-22 produced by the Th17 cells plays essential roles in various inflammatory diseases, such as experimental autoimmune encephalomyelitis, rheumato...
IL-37, a new member of the IL-1 cytokine family, is a natural inhibitor of innate immunity associated with autoimmune diseases. This study was undertaken to evaluate whether IL-37 has antiarthritic effects in patients with rheumatoid arthritis (RA) and in mice with collagen-induced arthritis (CIA). In this study, we analyzed the expression of IL-37 in PBMCs, serum, and lymphocytes from RA patie...
background: il-17 is a major cytokine player in t cell mediated leukocyte associated inflammation. il-17 is also recognized to participate in the pathophysiology of asthma. objective: to determine the role of il-17 in predicting severe asthma. methods: we obtained serum samples from asthmatic children under the age of 5-year in three different groups of mild (n=33), moderate (n=28) and severe (...
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