نتایج جستجو برای: il1rn
تعداد نتایج: 275 فیلتر نتایج به سال:
Background The interleukin-1 pathway has been linked to pancreatic diseases. We applied the Mendelian randomization approach explore whether higher receptor antagonist (IL-1RA) levels reduce risk of acute and chronic pancreatitis cancer. Methods Genetic variants associated with blood IL-1RA at genome-wide significance level located 5MB downstream or upstream IL1RN gene were extracted from a met...
The aim of this study was to clarify the association of IL-1RN variable number of tandem repeat (VNTR) polymorphism and H. pylori infection. We performed a meta-analysis of studies retrieved by systematic searches of Pubmed, Embase and the Cochrane Library. Data were analyzed with STATA 13.1 using pooled odds ratios (ORs) with 95% confidence intervals (CIs). A total of 18 studies were included ...
Besides its actions on the regulation of appetite, leptin has also been implicated in regulating reproductive and immune functions. Because leptin-deficient mice are more susceptible to lipopolysaccharide- and tumor necrosis factor-alpha-induced shock, which is associated with lower levels of interleukin 1 receptor antagonist (IL-1Ra), we investigated whether leptin is a direct regulator of IL-...
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