Abstract Background In 2022, the Simplified Endoscopic Mucosal Assessment for Crohn’s Disease (SEMA-CD) was created and internally validated, aiming to simplify endoscopic activity assessment in ileocolonoscopies CD. This score shown be easier faster apply than previously used Simple Score CD (SES-CD). our investigation, we aimed this on a European population assess if its prognostic value same...

Background & AimsVitamin D deficiency is common in Crohn’s disease (CD). High-dose vitamin had anti-inflammatory effects preclinical studies and trials of patients with CD. We performed a randomized trial to determine whether high-dose prevents postoperative recurrence CD after ileocolonic resection.MethodsPatients resection anastomosis were assigned randomly groups given weekly 25,000 IU oral ...

OBJECTIVE Assessment of disease extension and activity is crucial to guide treatment in Crohn's disease. The objective of the current cross-sectional study was to determine the accuracy of MR for this assessment. DESIGN 50 patients with clinically active (n = 35) or inactive (n = 15) Crohn's disease underwent ileocolonoscopy (reference standard) and MR. T2-weighted and precontrast and postcon...

BACKGROUND Crohn's disease is a relapsing, systemic inflammatory disease affecting the gastrointestinal tract with associated extraintestinal manifestations and immune disorders. Among the few cases reported, the association of Crohn's disease with polymyositis varies in its complexity and severity. We report here the first known case of inflammatory polymyositis leading to rhabdomyolysis in a ...

BACKGROUND AND AIM Pain and nausea are often reported during bowel cleansing (BC) for ileocolonoscopy (IC). We aimed to explore putative mechanisms associated with impaired tolerance to BC. METHODS A 1:1 (100 IBD and 100 controls) sex and age matched case-control study was performed. Patients completed the hospital anxiety and depression scale (HADS-A/HADS-D), visceral sensitivity index (VSI)...

S everal recent studies have identified an accelerating rate of radiation exposure in patients with poorly controlled complicated small bowel Crohn’s disease (CD), largely due to abdominal and pelvic computed tomography (CT) scans performed in local emergency departments with potentially long-term clinical consequences. This has motivated active research into alternatives for disease activity a...

BACKGROUND & AIMS The diagnostic role of Small Bowel Capsule Endoscopy (SBCE) in Crohn's Disease (CD) is under investigation. In a prospective study we investigated the diagnostic role of SBCE in patients with symptoms highly compatible with CD and undefined diagnosis after conventional techniques. METHODS From September 2005 to May 2009, all patients with clinically suspected CD and not conc...

Crohn's disease is a chronic inflammatory disorder affecting any part of the gastrointestinal tract, but frequently involves the small and large bowel. Typical presenting symptoms include abdominal pain and diarrhea. Patients with this disorder may also have extraintestinal manifestations, including arthritis, uveitis, and skin lesions. The PillCam™SB capsule is an ingestible disposable video c...

Abstract Background Intestinal Behçet's disease (BD) is a relapsing-remitting typically associated with punched-out ulcers in the ileocecal region. Optimal monitoring of activity necessary; however, ileocolonoscopy cannot be performed on regular basis as it invasive, resource-intensive and causes considerable patient discomfort. Furthermore, there are risks intestinal bleeding perforation cause...

abstract background ulcerative colitis (uc) is characterized by recurrent episodes of inflammation limited to the mucosal layer of the colon. calprotectin is a zinc and calcium binding protein derived from neutrophils and monocytes. it is easily detectable in tissue samples, body fluids, and stools, which makes it a potentially valuable marker of inflammation. the aim of the current study is to...