DNA biosensors (or genosensors) are analytical devices that result from the integration of a sequence-specific probe and a signal transducer. Among other techniques, electrochemical and piezoelectric methods have recently emerged as the most attractive due to their simplicity, low instrumentation costs, possibility for real-time and label-free detection and generally high sensitivity. Focusing ...

In this work, the effect of immobilization of bread yeast (Saccharomyces cerevisiae) by sol-gel technique combined with functionalized nanoporous silica was investigated in different weight ratios of silica containing materials (TMOS: LUS-1). The activities of immobilized yeast in days after immobilization were examined. The results showed immobilization maintain the yeast life for a longer tim...

Case Description- Five lions (one female and 4 male) were presented for diagnostic andsurgical treatment (wound management, castration and radiography). Immobilization oranesthesia was necessary to complete the procedure.Treatment and Outcome - Immobilization was induced using intramuscular injection ofvarious drug combinations (xylazine, diazepam or midazolam in combination withketamine). Inha...

Overview: Stereotactic Radiosurgery (SRS) is a distinct discipline that utilizes externally generated ionizing radiation in certain cases to inactivate or eradicate (a) defined target(s) in the head and spine without the need to make an incision. The target is defined by high-resolution stereotactic imaging. SRS typically is performed in a single session, using a rigidly attached stereotactic g...

Magnetic silica aerogel in hydrophobic and hydrophilic forms were used as support to immobilize Candida rugosa lipase by adsorption method. Response surface methodology (RSM) was employed to study the effects of the three most important immobilization parameters, namely enzyme/support ratio (0.3-0.5, w/w), immobilization time (60-120 min) and alcohol percentage (20-40, %v/v) on the specific act...

A microbial biosensor is an analytical device that immobilizes microorganisms onto a transducer for the detection of target analytes. With the development of nanotechnology, nanomaterials have been used to achieve better immobilization for developing a more reliable and selective microbial biosensor. Also, significant progress has been made in the development of transducer technology leading to...

We report the development and application of a microfluidic random access memory (RAM) that enables fully programmable formulation of an array of 95 nanolitre-scale reactions and subsequent random access to any reaction for addition of reagents or selective extraction of reaction products. This functionality is enabled by a novel droplet docking mechanism that exploits the physics of droplet fl...

A portable lensless imaging device combining light-emitting diodes (LEDs) and a CMOS image sensor was developed and its suitability for non-invasive live-cell in vitro monitoring of pancreatic islets was demonstrated. A microfluidic lab-on-a-chip platform containing micro wells with various depths was also fabricated and integrated into the optical sensor system, which allows for immobilization...

Here we report on the design and study of a biofuel cell consisting of a glucose oxidase-based anode (Aspergillus niger) and a laccasebased cathode (Trametes versicolor) using osmium-based redox polymers as mediators of the biocatalysts’ electron transfer at graphite electrode surfaces. The graphite electrodes of the device are modified with the deposition and immobilization of the appropriate ...

The aim of the present editorial is to briefly summarize the current scientific and technological accomplishments in the field of organic electronic biosensors as described in the articles published in this Special Issue. By definition, a biosensor is a robust analytical device that combines a biological recognition element (e.g., antibodies, enzymes, cells) with a transducer. Organic electroni...