Mass spectrometry imaging (MSI) is a powerful tool in metabolomics and proteomics for the spatial localization and identification of pharmaceuticals, metabolites, lipids, peptides and proteins in biological tissues. However, sample preparation remains a crucial variable in obtaining the most accurate distributions. Common washing steps used to remove salts, and solvent-based matrix application,...

The similarity between observed velocity structures of Al III and singly ionised species in damped Lyα systems (DLAs) suggests the presence of ionised gas in the regions where most metal absorption lines are formed. To explore the possible implications of ionisation effects we construct a simplified two-region model for DLAs consisting of an ionisation bounded region with an internal radiation ...

Electron-electron coincidence experiments have experienced over the past twenty years an increasingly rapid expansion and application to many different fields. Among them, the (e,2e) spectroscopy has been successfully used to investigate either the target electronic structure or the ionisation dynamics. The capability of this spectroscopy to investigate single particle properties in atoms, mole...

Two vertical cosmic ray telescopes for atmospheric cosmic ray ionisation event detection are compared. Counter A, designed for low power remote use, was deployed in the Welsh mountains; its event rate increased with altitude as expected from atmospheric cosmic ray absorption. Independently, Counter B’s event rate was found to vary with incoming particle acceptance angle. Simultaneous co-located...

The photoionisation spectrum of atomic phosphorus prepared by successive abstraction reactions involving H atoms and PH,, is presented from its ionisation threshold to 765 A. Prominent autoionisation structure is observed between the fine-structure limits 3P2-3P, near the ionisation threshold. In addition, a window resonance series is seen, involving inner s-shell excitation to. .. ('S)np 4P st...

A three dimensional Smoothed Particle Hydrodynamical (SPH) model has been extended to study the radiative driven implosion effect of massive stars on the dynamical evolutions of surrounding molecular clouds. The new elements in the upgraded code are the inclusion of Lyman continuum in the incident radiation flux and the treatment of hydrogen ionisation process; introducing ionisation heating & ...

Genotoxic carcinogens interact with nucleic acids and proteins to yield covalently bound products (adducts), the quantitative determination of which has been proposed as a biomonitor of human exposure to carcinogens. Mass spectrometry is playing a leading role both in the structural characterisation and in the quantitative determination of these carcinogen adducts. In particular electrospray io...

Here we report the first operation of a new apparatus of time of flight mass spectrometry using the tunable Vacuum-UV radiation emitted by a laser produced plasma as ionising source. Toluene cluster mass spectra acquired at different ionising wavelength are presented. Due to massive fragmentation the mass spectra change significantly by increasing the photon energy above the toluene ionisation ...