1. The metabolism of cis-indane-1,2-diol, trans-indane-1,2-diol, indene epoxide and 2-hydroxyindan-1-one in rats has been studied. The substances were administered to the animals by subcutaneous injection. 2. The urine of the dosed animals was examined for the presence of free and conjugated cis- and trans-dihydrodiols, and for each compound it was possible to isolate both cis and trans forms o...

The CD and UV spectra of (2S)-2,2'-spirobi[2H-benz[e]indene]1,1'(3H,3'H)-dione (2) and (IR,I'S,2S)-I,I',3,3'-tetrahydro-2,2'-spirobi[2H -benz[e]indene]-I,I' -diyl diacetate (3) were theoretical1y calculated by the application of the Jt-electron SCF-CI-DV MO method. The shape of component CD and UV bands was approximated by method (A) of the Gaussian distribution, or by method (B) employing the ...

The title compound, C(23)H(22)N(2), was obtained using the three-component imino Diels-Alder reaction via a one-pot condensation between anilines, α-pyridine-carboxy-aldehyde and indene using BF(3)·OEt(2) as the catalyst. The mol-ecular structure reveals the cis-form as the unique diastereoisomer. The crystal structure comprises one-dimensional zigzag ribbons connected via N-H⋯N hydrogen bonds....

Radiolabeled tracers can provide valuable information about the structure of and flux distributions in biocatalytic reaction networks. This method derives from prior studies of glucose metabolism in mammalian systems and is implemented by pulsing a culture with a radiolabeled metabolite that can be transported into the cells and subsequently measuring the radioactivity of all network metabolite...

In the title compound, C30H23N3O4, the central 1-methyl-pyrrolidine ring adopts a twist conformation on the N-CH2 bond. The pyrrolidin-2-one ring of the indolin-2-one ring system also has a twist conformation on the C-C bond involving the spiro C atom and the carbonyl C atom. The five-membered ring of the indene-1,3-dione moiety has an envelope conformation with the spiro C atom as the flap. Th...

The annulative coupling of secondary benzyl alcohols with internal alkynes efficiently proceeds in the presence a silver catalyst. reaction gives 1,2,3-substituted indene derivatives selectively as 1:1 products. procedure provides straightforward synthetic route to indenes from readily available starting materials upon treatment simple system under mild conditions.

A tandem 1,3-sulfur migration followed by iodocyclization reaction of propargylic sulfides in the presence NIS HFIP has been developed to synthesize indene-based β-iodoalkenyl sulfides. The choice media is crucial promote reaction. proposed mechanism involving initial activation and favoring sulfur starting thioether via cationic intermediates experimentally supported. In addition, suitability ...

Anaerobic microcosms constructed with soil from Guadeloupe, amended ethanol and acetone incubated anaerobically for more than a decade, transformed chlordecone (CLD) into suite of progressively dechlorinated products, including fully carboxylated indene product. This transformation product has never before been observed indicates that complete dechlorination CLD is possible. The was detected by...

A poly(3-hexylthiophene) (P3HT)-based inverted solar cell using indene-C60 bis-adduct (ICBA) as the acceptor achieved a high open-circuit voltage of 0.82 V due to ICBA's higher-lying lowest unoccupied molecular orbital level, leading to an exceptional power-conversion efficiency (PCE) of 4.8%. By incorporating a cross-linked fullerene interlayer, C-PCBSD, to further modulate the interface chara...