The separation of nine furanonaphthoquinones by micellar electrokinetic chromatography (MEKC) is described. The running electrolytes used in this method were 0.03 M sodium dodecyl sulphate (SDS) in 0.09 M borate buffer (pH 9) containing 10% methanol, with an applied voltage of 20 kV. Application of this technique in the determination of the main furanonaphthoquinones, 5-hydroxy-2-(1-hydroxyethy...

A new synthetic route to indeno[1,2-b]quinolines via reactions of o-propargylbenzaldehydes with N-aryl amines based on an intramolecular aza-Diels-Alder (Povarov) reaction has been developed. This method offers several advantages such as no requirement for an oxidant, high efficiency, and a wide reaction scope.

Methyl 1-aryl-3-cinnamoyl-4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates interact with 3-(arylamino)-1H-inden-1-ones to give the corresponding 1,1'-diaryl-3'-cinnamoyl-4'-hydroxy-1H-spiro[indeno[1,2-b]pyrrole-3,2'-pyrrole]-2,4,5'(1'H)-triones in good yields.

Indolo[2,1-b]quinazolin-6,12-dione (tryptanthrin) derivatives present important types of nitrogen-containing heterocyclic compounds which are useful intermediate products in organic synthesis and have potential pharmaceutical applications. The new ethyl 5-oxo-5-(((12-oxoindolo[2,1-b]quinazolin-6(12H)-ylidene)amino)oxy)pentanoate (Compound 2) was synthesized. Compound 2 is the first example a tr...

A metal-free, TBHP-promoted economical route is developed via the sp(2) C-H bond functionalization strategy for the synthesis of indenoquinolinones, 4-azafluorenones and fluorenones. Reactions provided excellent yield of the products under mild conditions. We have successfully synthesized 11H-indeno[1,2-b]quinolin-11-one, an antibacterial agent, in excellent yields.

The objective of the study was to determine the concentration of total PAHs and to identify the potential sources of contamination in sediments from the Romanian Black Sea sector. Sixteen priority polycyclic hydrocarbons were identified and determined quantitatively in samples of sediment collected from marine areas (depths over 20 m) from the 12 stations located between Sulina and Mangalia, du...

A method capable of determining 11 PAHs (acenaphthene, anthracene, benz[a]anthracene, benzo[a]pyrene, benzo[b]fluoranthene, benzo[k]fluoranthene, chrysene, phenanthrene, fluoranthene, indeno[1,2,3-cd]pyrene and perylene) in a mixture of 18 by second-derivative synchronous spectrofluorimetry in the constant wavelength mode was developed. It has not been possible to determine the following PAHs i...