vilsmeier-haack reaction of 2,3,3-trimethyl-3h-benzo[g]indole, then aqueous basic work-up, leads to benzo[g]indol-2-ylidene- malondialdehydes. these react with various arylhydrazines and quinolin-2-ylhydrazine to form 3,3-dimethyl-2-(1-aryl-1h-pyrazol-4-yl)- 3h-benzo[g]indoles in good yields.

Anavatanı Japonya olan Magnolia kobus DC., Magnoliaceae familyasından, kışın yaprağını döken küçük ağaç formunda bir bitkidir. Formu, aromatik yaprakları, bol miktarda açan pembemsi beyaz çiçekleri ve meyve güzelliği ile Peyzaj Mimarlığı bitkilendirme tasarımlarında tercih edilen bitkilerden biridir. Bu çalışmanın amacı, estetik özelikleri etkili bu bitkinin çelikle çoğaltılarak kentsel peyzajd...

The reductive metabolism of a series of 3-(indol-1-yl)-1,2-benzisoxazoles was examined in vitro using rat liver microsomes. 3-(Indol-1-yl)-1,2-benzisoxazole was reduced to the corresponding amidine (resulting from N-O bond cleavage) under anaerobic conditions. The reaction required viable microsomes and NADPH and was inhibited by carbon monoxide, air, and ketoconazole, suggesting the involvemen...

as an anti-angiogenesis agent by Ladouceur et al. These compounds have a potent inhibitory effect on the growth of tumor cells with angiogenesis activity. We have also carried out a structure–activity relationship (SAR) study of 3-(indol2-yl)quinoxalin-2-ones, which showed a potent inhibitory activity toward the VEGF-induced proliferation of human mesangial cells and the VEGF-induced auto-phosp...