Propofol, one of the most commonly used intravenous anesthetic agents, has been reported to have anti-inflammatory property. However, the anti-allergic inflammation effect of propofol and its underlying molecular mechanisms have not been elucidated. In the present study, we aim to investigate the roles of NF-kB activation in propofol anti-asthma effect on OVA-induced allergic airway inflammatio...

Studying associations between sibship characteristics and allergic diseases in detail may contribute clues to their etiology. The authors studied associations between sibship characteristics and risk of self-reported allergic rhinitis and asthma among 31,145 pregnant women participating in a nationwide study in Denmark during 1997-2000. Increasing sibship size was associated with a decreased ri...

the purpose of the present study is to investigate the prevalence of th17 and regulatory t (treg) cells in children with allergic rhinitis (ar) accompanying with bronchial asthma (ba).24 children with ar, 22 children with ba, 18 children with ar accompanying with ba,and 20 healthy controls were recruited. the prevalence of peripheral blood th17 and treg cells were determined by flow cytometry. ...

Epidemiological studies suggest an inverse relationship between helminth infections and allergic disease, and several helminth-derived products have been shown to suppress allergic responses in animals. This study was undertaken to evaluate the effect of a crude extract of Caenorhabditis elegans on allergic airway inflammation in a murine model of asthma. Allergic airway inflammation was induce...

BACKGROUND A clinically relevant relationship between classic asthma and allergic rhinitis has been reported. However, the possible link between cough variant asthma (CVA) and allergic rhinitis remains unknown. OBJECTIVES To clarify the prevalence and clinical relevance of perennial allergic rhinitis or seasonal allergic rhinitis in CVA patients compared to classic asthma patients. METHODS ...

Picrasma quassioides (D.Don) Benn. (PQ) is used in traditional medicine for the treatment of inflammatory conditions, including gastritis. This study aimed to evaluate the inhibitory effects of PQ on the inflammatory responses in mice with allergic asthma induced by ovalbumin (OVA) and in lipopolysaccharide (LPS)‑stimulated RAW264.7 cells. To induce allergic asthma, the mice underwent OVA sensi...

Objective(s): Allergic Asthma is an inflammatory disease of the lungs that is characterized by increased infiltration of leukocytes into the airways, limiting the respiratory function. Studies suggest that a defective general regulatory system against inflammation could be a significant factor in allergic asthma. It has been shown that Mesenchymal stem cells (MSCs) have a cellular immunosuppres...

In the present study, ethanolic extract of Mesua ferrea L. stamens was investigated for its potential to reverse some features bronchial asthma in ovalbumin-induced murine model asthma. commonly called nagakeshar (Family, Calophyllaceae) is a well-known antiallergic drug Asian folk system medicines. work, pharmacological studies are done provide scientific evidence therapeutic plants allergic A...

Aspergillosis of the respiratory tract has diverse manifestations that range from hypersensitivity disorders to rapidly invasive disseminated disease. These can be classified into 3 distinct clinical categories, viz. allergic aspergillosis, saprophytic colonization, and invasive aspergillosis (Table 1). Different presentations of the allergic form, usually seen in atopic individuals, include As...

Background Asthma is a chronic inflammatory disease induced by Type 2helper T cells (Th2) and eosinophils. Vascular cell adhesion molecule-1(VCAM-1) is the regulatory receptor implicated with recruiting eosinophils andlymphocytes to pathologic site in asthma. A monoclonal antibody (mAb)against VCAM-1 may attenuate allergic inflammation and pathophysiologicfeatures of asthma. Weevaluated whether...