نتایج جستجو برای: induced malaria
تعداد نتایج: 1024341 فیلتر نتایج به سال:
Introduction: Malaria is among the most significant travel-related infections encountered by travelers to endemic countries in terms of morbidity and mortality. In Qatar, imported malaria has increased over the last 5 years; 493 travel-related cases were confirmed in 2016. In the current study, the knowledge of malaria chemoprophylaxis among physicians in the State of Qatar was...
Levels of soluble Fas ligand (sFasL) in serum were elevated in patients with Plasmodium falciparum malaria and showed a significant decline during disease course. sFasL levels that were elevated before antimalarial treatment began correlated significantly with depressed total lymphocyte and T-cell counts. These data suggest that Fas-induced apoptosis might play a role in malaria-associated lymp...
INTRODUCTION The complexity of immunity to malaria is well known, and clear correlates of protection against malaria have not been established. A better understanding of immune markers induced by candidate malaria vaccines would greatly enhance vaccine development, immunogenicity monitoring and estimation of vaccine efficacy in the field. We have previously reported complete or partial efficacy...
Plasmodium falciparum malaria remains a major public health threat for which there is no licensed vaccine. Abs play a key role in malaria immunity, but Ab-mediated protection is only acquired after years of repeated infections, leaving children in endemic areas vulnerable to severe malaria and death. Many P. falciparum Ags are extraordinarily diverse and clonally variant, which likely contribut...
Following infection by the malaria parasite, Plasmodium falciparum, human erythrocytes show increased permeability to a variety of low molecular weight solutes. In this study a number of anion transport blockers were identified as potent inhibitors of the transport of a wide range of solutes into human erythrocytes infected in vitro with P. falciparum. 5-Nitro-2-(3-phenyl-propylamino)benzoic ac...
Malaria infection is accompanied by increased production of reactive oxygen species which indicates the environment for oxidative stress. Oxidative stress in malaria may originate from several sources including intracellular parasitized erythrocytes and extra-erythrocytes as a result of haemolysis and host response. The aim of this study is to estimate level of stress induces by malaria parasit...
Background and Objective: Malaria is a disease affecting 300–500 million people in tropical and subtropical regions and causes approximately 2.7 million deaths annually. Currently, no vaccine protects against malaria and resistance to anti-malaria drugs such as chloroquine is increasing and spreading geographically. Moreover, anti-malarial drugs are expensive and often unaffordable to low-incom...
The fight against malaria is currently ongoing in many countries where the disease is still endemic. The overall target is to eliminate malaria in all nations, regardless of their malaria burden, by 2030. Currently, the disease has been eliminated mainly in low-burden and unstable malaria areas globally. However, in high-burden countries, particularly in Africa, the disease is still not elimina...
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