When portions of a sound are replaced by a potential masker, the missing fragments may be perceptually restored, resulting in apparent continuity of the interrupted signal. This phenomenon has been examined extensively by using pulsation threshold, auditory induction, and phonemic restoration paradigms in which two sounds, the inducer and the inducee, are alternated (ABABA...), and the conditio...

Effects of cell density, symbiotic plasmid and mutation (by transposon mutagenesis) on the expression of rhi genes in Rhizobium leguminosarum biovar viciae were studied. Strains of the bacterium bearing and lacking regulatory gene rhiR were grown to late exponential phase and assayed for the production of rhi genes inducer. R. leguminosarum biovar viciae was specific for the synthesis of the rh...

Temperature-sensitive mutants of vaccinia virus, with genetic changes that map to the open reading frame encoding the F10 protein kinase, exhibit a defect at an early stage of viral morphogenesis. To further study the role of the enzyme, we constructed recombinant vaccinia virus vF10V5i, which expresses inducible V5 epitope-tagged F10 and is dependent on a chemical inducer for plaque formation ...

Lipoteichoic acid from Staphylococcus aureus was a potent inducer of procoagulant activity in isolated mononuclear cells but not in whole blood. In contrast, staphylococcal peptidoglycan showed equal levels of potency in isolated mononuclear cells and whole blood, suggesting that peptidoglycan is an important inducer of procoagulant activity in severe sepsis involving gram-positive bacteria.

Inducible expression systems are widely employed for the titratable control of gene expression, yet molecules inadvertently present in the growth medium or synthesized by the host cells can alter the response profile of some of these systems. Here, we explored the quantitative impact of these residual inducers on the apparent response properties of inducible systems. Using a simple mathematical...

We report two types of signal enhancement strategy derived from the origin of mechanical response, surface stress and mass, of the dynamic mode microcantilever for the detection of PSA at low picogram scales (low femtomolar concentration). The PSA detection at extremely low concentration levels is crucial to the early detection of relapses of prostate cancer after the radical prostatectomy and ...

Friend erythroleukemia cells temperature-sensitive (ts) for growth have been used to study the cell-cycle dependence of erythroid differentiation. ts cells accumulated hemoglobin in response to inducer when replicating optimally at permissive temperatures. However, when arrested in the G1 phase of the cell cycle at a nonpermissive temperature, ts cells did not accumulate hemoglobin or globin mR...