Prediction of diseases would help physicians to make informal decision regarding the type of treatment. Jaundice is the most common condition that requires medical attention in newborn babies. Although most newborns develop some degree of jaundice, a high level bilirubin puts a newborn at risk of bilirubin encephalopathy and kernicterus, which are rare but still occur in Egypt. This paper prese...

Newbornswith jaundice or unrecognized hyperbilirubinemia are a vulnerable population which is likely to be deprived from preventive and/or therapeutic healthcare services in their transition from birthing hospital to their homes. Of the 4million infants born each year in the United States, over 3.5 million are born at 35 or more weeks of gestation. Most have benign outcomes with little or no th...

Inspissated bile syndrome (IBS) is a rare condition in which thick intraluminal bile, including bile plugs, sludge, or stones, blocks the extrahepatic bile ducts in an infant. A 5-week-old female infant was admitted for evaluation of jaundice and acholic stool. Diagnostic tests, including ultrasound sonography, magnetic resonance cholangiopancreatography, and a hepatobiliary scan, were not conc...

One of the goals of Healthy People 2010 (set in 1998) was to reduce preterm birthrates from 11.6% to 7.6%. However, in 2004, the preterm birthrate of 12.5% was actually higher than the rate in 1998. Approximately 65% of this increase in prematurity rate is attributed to the increasing birthrate of the late preterm infant. Care of the late preterm infant is far more complicated than many hospita...

hyperbilirubinemia is a common problem during neonatal period especially in preterm neonates. transcutaneous bilirubin measurement (tcb) by special devices had been documented as an effective tool for predicting neonatal jaundice in full term neonate, but for preterm infants the present evidences are controversial. we carried out a prospective study in shariati hospital nicu. 126 paired tcb/tot...

Galactosemia is an autosomal recessive disorder, which caused by a deficiency of one of three enzymes that involved in the metabolism of galactose; galactokinase (GALK), galactose-1-phosphate uridyltransferase (GALT) and uridine-diphosphate galactose-4’epimerase (GALE). Clinical manifestations including poor feeding, jaundice, hepatomegaly, vomiting, hypoglycemia, convulsions, failure to thrive...

Syphilis infection has re-emerged after years of declining incidence. The prevalence of congenital syphilis (CS) has increased in Korea and other countries during the last few decades. Untreated infants develop symptoms such as rhinorrhea, anemia, jaundice, cutaneous lesions, hepatosplenomegaly, and pseudoparalysis within weeks or months. Significant renal disease is uncommon in CS, and clinica...

OBJECTIVE To test whether the combined use of total plasma/serum bilirubin (TSB) levels and clinical risk factors more accurately identifies infants who receive phototherapy than does the use of either method alone. STUDY DESIGN We recruited healthy infants of ≥35 weeks' gestation at 6 centers that practiced universal predischarge TSB screening. Transcutaneous bilirubin (TcB) was measured at ...

In spite of the frequency of icterus neonatorum and the work done to elucidate the problems connected with it, there still remains much divergence of opinion regarding its incidence and pathogenesis. Estimates of the incidence vary from 40 to 80 per cent. of the nYewborn. Since the detection of jaundice is influenced by many factors, such as the vascularity of the skin and the nature of the lig...