Infantile hemangioma is a benign endothelial tumor composed of disorganized blood vessels. It exhibits a unique life cycle of rapid postnatal growth followed by slow regression to a fibrofatty residuum. Here, we have reported the isolation of multipotential stem cells from hemangioma tissue that give rise to hemangioma-like lesions in immunodeficient mice. Cells were isolated based on expressio...

Infantile hemangiomas are the most common vascular tumors in childhood. In view of its proven effectiveness in such cases, propranolol is the drug of choice. We present the case of a male infant who started treatment with propranolol shortly after birth due to heart disease. After 7 months, when the patient had suffered various respiratory exacerbations, this treatment was suspended. One week l...

Familial infantile myasthenia is an autosomal recessive disorder, recently classified as congenital myasthenic syndrome type Ia. Onset of symptoms is at birth to early childhood with significant myasthenic weakness and possible respiratory distress, followed later in life by symptoms of mild to moderate myasthenia. Thirty-six patients of 12 families, seven of them consanguineous, were used to m...

hemangiopericytoma is a rare vascular tumor observed mostly in adults. it usually presents with a painless slowly enlarging mass. the infantile type with much rarer occurrence has a different course compared to adults. very few case reports have been described in the literature with disease onset in the infancy. the first reported case of infantile hemangiopericytoma of limbs from the middle ea...

Dtiring the first year of life, diffuse corneal clouding is usually caused by infantile glaucoma or infections and inflammatory processes. Although several of the mucopolysaccharidases may also cause corneal clouding, other signs and symptoms predominate. Maumenee* described a congenital, hereditary corneal dystrophy characterized by diffuse corneal edema during the first year of life. His repo...

Almost as far back as written records go we find evidence that mankind has been afflicted by frequent recurrences of horrible epidemics. Periodically occurring without any apparent cause, each one has taken its toll of life and then departed as strangely as it came. They have halted social progress, determined the results of wars, and sometimes even threatened the existence of civilization itse...

A 27-year-old man with severe infantile kyphoscoliosis suffered from recurrent respiratory tract infections during childhood and early adult life. He deteriorated and was found to have pernicious anaemia and common variable immunodeficiency with hypogammaglobulinaemia and impairment of cell-mediated immunity. Marked clinical improvement has followed the institution of effective gamma-globulin r...