Varicocele is one of the leading causes of male infertility, and is present in almost 40% of infertile males. Recent understanding of the role of oxidative stress in male reproduction has led some researchers to postulate oxidative stress as the possible cause of sperm dysfunction in varicocele patients. The objective of the present study was to examine the published literature on the role of o...

About infertility Infertility is the inability of a couple to get pregnant despite having regular unprotected sex. A couple is regarded as infertile if, after regular sexual intercourse, they have not conceived in two years. It is estimated that one in seven UK couples has difficulty conceiving (HFEA, 2006). Identifiable causes of infertility include: ovulatory disorders in 27% of couples; tuba...

OBJECTIVE This observational, retrospective study investigated infertility among Iraqi men who had been long-term prisoners of war. METHODS Routine seminal fluid analyses were undertaken in former prisoners with suspected infertility attending the Ramadi Infertility Clinic, Ramadi, Iraq; semen samples were also microscopically evaluated in these patients. RESULTS In 16 out of 38 patients (...

Historical data in the 1950s suggests that 7%, 11%, 33%, and 87% of couples were infertile by ages 30, 35, 40 and 45, respectively. Up to 22.3% of infertile couples have unexplained infertility. Oxidative stress is associated with male and female infertility. However, there is insufficient evidence relating to the influence of oxidative stress on the maintenance of a viable pregnancy, including...

Endometriosis is a complex, inflammatory disease that affects 6-10% of reproductive-aged women. Almost half of the women with endometriosis experience infertility. Despite the excessive prevalence, the pathogenesis of endometriosis and its associated infertility is unknown and a cure is not available. While many theories have been suggested to link endometriosis and infertility, a consensus amo...

Human infertility has been increasing worldwide but the exact causes are not yet known. Male infertility, which currently accounts for approximately half of all cases, has been increasing faster than female. While certain cases of male infertility are due to anatomical abnormalities, an estimated 40-49% of cases are due to deficient sperm production of unidentifiable origin. There is growing bo...

A. Agarwal et al. (eds.), Studies on Men’s Health and Fertility, Oxidative Stress in Applied Basic Research and Clinical Practice, DOI 10.1007/978-1-61779-776-7_24, © Springer Science+Business Media, LLC 2012 Abstract Male infertility affects 40% of infertile couples in the USA and may be attributed to conditions such as varicocele, leukocytospermia, infection, and idiopathic infertility. Such ...

PCOS, the leading cause of anovulatory infertility that affects up to one fifth of the female population, is a complex chronic disease of genetic as well as environmental determination, but still unclear etiology. Besides of infertility, PCOS leads to menstrual dysfunctions, hirsutism and obesity--symptoms that are known to cause profound psychosocial distress. The present paper review the prob...

The use of antioxidants is now often used as a pharmacological adjunct to limit infertility. Indeed, the lay public rightly perceives oxidative stress and, thus, antioxidant treatment as important modulators of infertility. While the direct effects of antioxidant treatment on the quality of semen and oocytes are still under investigation, a significant body of evidence points to loss of vascula...