introduction: atrial fibrillation (af) is the most prevalent cardiac arrhythmias that cardiologists and internists encounter. the goal of this article is to clarify an overview of the evidence linking inflammation to af existence, which may highlight the effect of some pharmacological agents that have genuine potential to reduce the clinical burden of af by modulating inflammatory pathways. mat...

objective: triptolide, the active component of tripterygium wilfordii hook f has been used to treat autoimmune and inflammatory conditions for over two hundred years in traditional chinese medicine. however, the processes through which triptolide exerts immunosuppression and anti-inflammation are not understood well. in this review, we discuss the autoimmune disorders and inflammatory condition...

objective: premna integrifolia linn (family: verbenaceae) synonym of premna serratifolia has tremendous medicinal value. preliminary pharmacological studies were performed on the methanolic extract of premna integrifolia (mepi) bark to investigate neuropharmacological, analgesic, and anti-inflammatory activities. materials and methods: neuropharmacology study was done by open field and hole cro...

sulfur mustard, a bifunctional alkylating agent, causes severe eye injury. the injury is a result of late inflammation, which is mediated by prostaglandins. theoretically, inhibition of prostaglandins by reagents such as indomethacine could result in alleviation of clinical adverse effects. in this study, the protective effect of topically applied indomethacine against sulfur mustard toxicity w...

conclusions there was no difference in clinical outcome after cardiac surgery when we administered an additional dose of methylprednisolone compared to a single dose of methylprednisolone. patients and methods sixty pediatric patients (age < 5years) undergoing cardiopulmonary bypass surgery between september 2011-2012 at imam reza hospital-mashhad were randomly assigned to receive preoperative ...

considering the high prevalence of osteoarthritis (oa) and since until now there has not been any human studies to evaluate the effect of sesame in oa patients, this study was designed to assess the effect of administration of sesame on inflammation and oxidative stress in patients with knee oa. fifty patients with knee oa were allocated into two groups namely control and sesame group. 25 patie...

background management of urethral stricture has evolved over the years with better understanding of the pathology, advancement in imaging, and introduction of several techniques of urethral reconstruction. in sub-saharan africa, advancement in management of urethral stricture may not be comparable with what obtained in most developed nations because of problems like late presentation and persis...

objective: atherosclerosis disease, inflammation and malnutrition have strong association with end stage renal disease (esrd). diabetes mellitus (dm) is the most commonly esrd causes. diabetic nephropathy (dn) could be associated with inflammation. type 2 diabetic patients with advanced nephropathy show the highest levels of inflammatory markers. this study was designed to determine the associa...

background: rheumatoid arthritis is a type of inflammatory pain and is an autoimmune and chronic inflammatory disease which can lead to hyperalgesia, edema and decreased motor activity in affected area. mesenchymal stem cells conditioned medium (msc-cm) has anti-inflammatory mediators which can regulate the immune responses, alleviate inflammatory symptoms and has a paracrine effects too. the a...