نتایج جستجو برای: inflammatory linear verrucous epidermal nevus
تعداد نتایج: 796676 فیلتر نتایج به سال:
Epidermal nevus syndrome (ENS) is a rare condition characterized by congenital epidermal nevi (EN) associated abnormalities of other organs including central nervous system (CNS), skeletal system, eyes, and oral cavity (1). ENS is divided into a group of distinct disorders, based on the associated epidermal nevus and genetic inheritance pattern. Organoid nevus could be seen in some ENS, includi...
Aim. Secondary tumor rarely develops from epidermal nevus. We present a case of a metastasizing squamous cell carcinoma that developed in a solitary epidermal nevus. Case Report. An 82-years old Japanese female was presented with a red tumor on the left axilla. She reported that the tumor developed in a congenital epidermal nevus. A biopsy of the tumor showed that a well-differentiated squamous...
Epidermal naevi are hamartomas that are characterized by hyperplasia of the epidermis and adnexal structures and may be associated with serious disfiguration. Management of epidermal naevi is challenging. We present here our experience with cryosurgery in the treatment of verrucous epidermal naevi. The aim of this study was to determine the efficacy and safety of cryosurgery for the treatment o...
OTULIN is a deubiquitinase that specifically cleaves linear ubiquitin chains. We demonstrate ablation of selectively in keratinocytes, results the appearance inflammatory skin lesions develop into verrucous carcinomas. Genetic TNFR1, knockin expression kinase-inactive RIPK1 or keratinocyte-specific deletion FADD and MLKL completely rescues mice with deficiency from dermatitis tumorigenesis, ide...
Nevus comedonicus is an uncommon variant of adnexal hamartoma and is considered a rare subtype of epidermal nevi. It was first described in 1895 by Kofmann who used the term “comedo-nevus”. It manifests as a group of closely dilated follicular openings with dark keratin plugs resembling comedones. Both unilateral and bilateral distributions are seen. The face is the most commonly affected site ...
We demonstrate that ablation of OTULIN, a deubiquitinase specifically cleaves linear ubiquitin chains, selectively in keratinocytes, results the appearance inflammatory skin lesions develop into verrucous carcinomas. Genetic TNFR1, knockin expression kinase-inactive RIPK1 or keratinocyte-specific deletion FADD and MLKL completely rescues mice with OTULIN deficiency from dermatitis tumorigenesis...
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